Results 71 to 80 of about 142,634 (260)

Use and misuse of the concepts of tradition and property rights in the conservation of natural resources in the atlantic forest (Brazil) Uso e abuso dos conceitos de tradição e direitos de propriedade na conservação de recursos naturais na Mata Atlântica, Brasil

Ambiente & Sociedade, 2006
The relationship between resource management, local populations, and property regimes has long puzzled researchers and policy-makers. The constant failure of conservation policy reliant upon privatization and statization, has led both policy makers and ...
Fábio de Castro, Andréa D. Siqueira, Eduardo S. Brondízio, Lúcia C. Ferreira   +3 more
doaj   +1 more source

A minimal cellulosome‐like system in Cellulosilyticum lentocellum

FEBS Open Bio, EarlyView.
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan, Amias Alstrom‐Moore, Gary W Black   +2 more
wiley   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

Diversity of bryophytes in priority areas for conservation in the Atlantic forest of northeast Brazil

Acta Botânica Brasílica, 2015
The northeastern Brazilian Atlantic forest is the region with the greatest diversity of bryophytes in the country. However, knowledge about bryophytes is irregularly distributed among Brazilian regions.
Mércia Patrícia Pereira Silva, Kátia Cavalcanti Pôrto   +1 more
doaj   +1 more source

Blood RNA Biomarker Signatures for Early Diagnosis and Prognosis in Ischemic and Hemorrhagic Stroke: The IBIS‐CT1 Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the expression of nine blood RNA biomarkers in a clinical trial based on genes previously identified in an experimental monkey model of stroke for diagnosis feasibility and prognostication. Methods IBIS‐CT1 was a prospective longitudinal study enrolling patients with ischemic stroke (IS) or intracerebral hemorrhage (ICH ...
Salomé Retailleau, Marie Bruguet, Irina Viakhireva‐Dovganyuk, François‐Mathias Merrien, Denis Marechal, Aurore Jourdain, Philippe Goas, Jordan Coris, Julien Asselineau, Maëlys Consigny, Gérald Le Gac, Serge Timsit   +11 more
wiley   +1 more source

Pan-Plastome Evolution and Metabolite Variation Provide Insights to Conservation of the Tibetan Medicinal Plant Mirabilis himalaica

Plants
Mirabilis himalaica is an endemic Tibetan medicinal plant distributed from the Western Himalaya to the Hengduan Mountains, highly regarded for its abundant flavonoids.
Yuxuan He, Nan Lin, Beier Duan, Jinhao Wang, Xiankun Wang, Zeyuan Cao, Song Song   +6 more
doaj   +1 more source

Brazilian Cerrado and Conservation Units

Revista de Gestão Social e Ambiental
Objective: The present study aims to demonstrate the importance of the Brazilian cerrado, and its preservation through Conservation Units (UC’S).   Theoretical Framework: The cerrado is home to one of the main components of Brazilian fauna and flora and is considered one of the twenty-five global hotspots.
Lidiane Lopes Arriel Mendonça, Eumar Evangelista de Menezes Júnior   +1 more
openaire   +1 more source

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem, Noa Bielopolski, Vijai Krishnan, Shane Wald‐Altman, Shelly I Shrian, Omer Bar‐Yosef, Livia Kapusta, Claire Shamber, Patricia L. Musolino, Miguel Weil   +9 more
wiley   +1 more source

Malha rodoviária e conflitos de conservação alha no cerrado: um estudo para a preservação de anfíbios = Road network and conservation conflicts in cerrado: a study for amphibian preservation

Acta Scientiarum: Biological Sciences, 2006
A criação de unidades de conservação tem sido uma importante ferramenta para minimizar a perda de biodiversidade. Entretanto, a alocação destas unidades deve ser otimizada de forma que possam preservar o maior número de espécies sob uma série de ...
Rodrigo de Jesus Silva, Ludgero Cardoso Galli Vieira, Míriam Plaza Pinto, Guilherme Oliveira, Bruno Souza Barreto   +4 more
doaj  

Artificial Intelligence in Systemic Sclerosis: Clinical Applications, Challenges, and Future Directions

Arthritis Care &Research, EarlyView.
Systemic sclerosis (SSc) is a rare autoimmune disease defined by immune dysregulation, vasculopathy, and progressive fibrosis of the skin and internal organs. Despite advances in care, major complications such as interstitial lung disease (ILD) and myocardial involvement remain the leading causes of morbidity and mortality.
Cristiana Sieiro Santos, José Miguel Sequí‐Sabater, Diego Benavent   +2 more
wiley   +1 more source