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Frontiers in Pharmacology, 2023 Purpose: HSK16149 is a novel, potent gamma-aminobutyric acid (GABA) analog for the treatment of neuropathic pain. This study aimed to evaluate the safety, tolerability, and pharmacokinetics of HSK16149 after single and multiple doses in healthy Chinese ...
Qian Chen +28 more
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EBioMedicine, 2023 Summary: Background: We assessed the safety and immunogenicity of a core–shell structured lipopolyplex (LPP) based COVID-19 mRNA vaccine, SW-BIC-213, as a heterologous booster in healthy adults.
Yu-Zhou Gui +22 more
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Soft Computing, 2021 AbstractWe introduce so-called consistent posets which are bounded posets with an antitone involution$$'$$′where the lower cones of$$x,x'$$x,x′and of$$y,y'$$y,y′coincide provided thatx, yare different from 0, 1 and, moreover, ifx, yare different from 0, then their lower cone is different from 0, too.
Ivan Chajda, Helmut Länger
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On Grid Quorums for Erasure Coded Data
Entropy, 2021 We consider the problem of designing grid quorum systems for maximum distance separable (MDS) erasure code based distributed storage systems. Quorums are used as a mechanism to maintain consistency in replication based storage systems, for which grid ...
Frédérique Oggier, Anwitaman Datta
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Time-Consistent and Market-Consistent Evaluations [PDF]
SSRN Electronic Journal, 2011 We consider evaluation methods for payoffs with an inherent financial risk as encountered for instance for portfolios held by pension funds and insurance companies. Pricing such payoffs in a way consistent to market prices typically involves combining actuarial techniques with methods from mathematical finance.
Mitja Stadje, Antoon Pelsser
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Remote Sensing, 2021 The space segment of all the five satellite systems capable of providing precise position services, namely BeiDou Navigation Satellite System (BDS) (including BDS-3 and BDS-2), Global Positioning System (GPS), GLObal NAvigation Satellite System (GLONASS),
Xuanping Li, Lin Pan
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The influence of slag content on the mechanical properties of high-strength concrete [PDF]
Archives of Civil EngineeringIn light of the current situation where excessive amounts of excavated earth from subway tunnel construction are being stacked with low utilization and value, this study used residue as a mineral admixture to investigate the effects of different ...
Xiaochun Zhao, Meijiu Zhao
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Journal of Harbin University of Science and Technology, 2020 In order to accurately study the consistency between the door and the Bpillar during the collision process and better analyze the influence of the deformation of the front and rear doors on the B column deformation during the side collision of the door
WU Shi, ZHAO Hong-wei
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AIMS Mathematics, 2022 In this paper, we study the problem of simultaneous variable selection and estimation for longitudinal ordinal data with high-dimensional covariates. Using the penalized generalized estimation equation (GEE) method, we obtain some asymptotic properties ...
Xianbin Chen, Juliang Yin
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Putting consistency back into eventual consistency [PDF]
Proceedings of the Tenth European Conference on Computer Systems, 2015 Geo-replicated storage systems are at the core of current Internet services. The designers of the replication protocols used by these systems must choose between either supporting low-latency, eventually-consistent operations, or ensuring strong consistency to ease application correctness.
Balegas, Valter +6 more
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