Molecular Oncology, EarlyView.A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath +13 more
wiley +1 more source
Vaginal lavage fluid can serve as a reliable method for early screening of endometrial cancer: a proof-of-concept study. [PDF]
Front OncolLi Y, Ren P, Huang J, Tan S, Wang N.
europepmc +1 more source
Hybridoma growth in a new generation hollow fibre bioreactor: antibody productivity and consistency [PDF]
, 1997 N. Kessler +4 more
openalex +1 more source
YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma
Molecular Oncology, EarlyView.The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy +9 more
wiley +1 more source
Semi-Supervised Object Detection: A Survey on Progress from CNN to Transformer. [PDF]
Sensors (Basel)Shehzadi T +4 more
europepmc +1 more source
Emerging role of ARHGAP29 in melanoma cell phenotype switching
Molecular Oncology, EarlyView.This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster +3 more
wiley +1 more source
Translation, cross-cultural validity and reliability of a Danish version of the Banff Patella Instability Instrument 2.0 (BPII 2.0). [PDF]
J Exp OrthopNielsen TG +3 more
europepmc +1 more source
A Total Variation Denoising Method Based on Median Filter and Phase Consistency [PDF]
, 2020 Shuo Huang, Suiren Wan
openalex +1 more source
Molecular Oncology, EarlyView.In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern +7 more
wiley +1 more source
Optimizing regional innovation ecosystems through actor-environment coevolution: A dynamic configurational analysis from a CAS perspective. [PDF]
PLoS OnePang H, Jiang Y, Wu L, Wang L.
europepmc +1 more source