Aging Resources and Vulnerability Across Targets: Self-Other Profiles in Israeli and Japanese Assisted-Living Residents. [PDF]
J Cross Cult GerontolBodner E +11 more
europepmc +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Multidimensional adversity burden predicts functional deterioration and reduced maintenance of independence in middle-aged and older adults. [PDF]
Medicine (Baltimore)Rong J, Chen W.
europepmc +1 more source
Specification Tests Based on Artificial Regressions [PDF]
Many specification tests can be computed by means of artificial linear regressions. These are linear regressions designed to be used as calculating devices to obtain test statistics and other quantities of interest.
Russell Davidson, James G. MacKinnon
core
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Kolmogorov-Smirnov-type test for dependently double-truncated durations: A copula approach. [PDF]
Lifetime Data AnalToparkus AM, Weißbach R.
europepmc +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Influence of sarcopenia on functional independence and depression in older adults: a cross-sectional study. [PDF]
J Exerc RehabilYoon TH, Jee YS.
europepmc +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Cross-cultural adaptation and validation of the Arabic version of the Edmonton Frail Scale among Saudi community-dwelling older adults: A cross-sectional study. [PDF]
Medicine (Baltimore)Alshahrani AM +9 more
europepmc +1 more source