The ubiquitin system in normal and infected germinal center B cells
FEBS Letters, EarlyView.The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis +2 more
wiley +1 more source
Globalization and the Output-Inflation Tradeoff: New Time Series Evidence [PDF]
Recent cross-country studies on the globalization and output-inflation tradeoff correlation find openness has no significant effect on OECD countries. Those studies assume parameter constancy across countries. In this paper, we argue that this assumption
Eijffinger, S.C.W., Qian, Z.
core
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Development and Validation of a Sitting-Balance Confidence Scale for Individuals with Spinal Cord Injury. [PDF]
Healthcare (Basel)Barfield JP +4 more
europepmc +1 more source
Do People (Want to) Plan? [PDF]
Central to many theoretical accounts of the process by which (rational) people tackle dynamic decision problems is the concept of a plan: a set of conditional decisions as to what would be decided under certain conditions (imposed by Nature).
John Hey
core
FEBS Letters, EarlyView.Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley +1 more source
Disease-nonspecific Activity Outcome Measures for Adult Rehabilitation Populations: A COSMIN-based Systematic Review of Psychometric Properties. [PDF]
Prog Rehabil MedKinoshita S +8 more
europepmc +1 more source
Victory and Defeat in a Model of Behavior in Games and Toward Risk [PDF]
The standard expected utility model is augmented by allowing individuals to receive additional utility in states in which they consider themselves victorious and to lose a utility increment in which they consider themselves defeated.
William S. Neilson
core
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
How strong is the administrative backbone of ethical governance? A descriptive cross-sectional study of health research ethics committees in Tanzania. [PDF]
BMJ OpenHaule LAS, Aboud M, Mloka D.
europepmc +1 more source