Results 71 to 80 of about 1,190,358 (265)

Datalog± Ontology Consolidation [PDF]

open access: yes, 2016
Knowledge bases in the form of ontologies are receiving increasing attention as they allow to clearly represent both the available knowledge, which includes the knowledge in itself and the constraints imposed to it by the domain or the users.
Deagustini, Cristhian Ariel David   +3 more
core   +1 more source

On Integrating Fuzzy Knowledge Using a Novel Evolutionary Algorithm [PDF]

open access: yesProcs. of the IEEE 10th International Conference on Computer & Information Technology (ICCIT 2007), pp. 38-43, Dhaka, Bangladesh, December 27-29, (2007), 2013
Fuzzy systems may be considered as knowledge-based systems that incorporates human knowledge into their knowledge base through fuzzy rules and fuzzy membership functions. The intent of this study is to present a fuzzy knowledge integration framework using a Novel Evolutionary Strategy (NES), which can simultaneously integrate multiple fuzzy rule sets ...
arxiv   +1 more source

Characteristics of the Kelch domain containing (KLHDC) subfamily and relationships with diseases

open access: yesFEBS Letters, EarlyView.
The Kelch protein superfamily includes 63 members, with the KLHDC subfamily having 10 proteins. While their functions are not fully understood, recent advances in KLHDC2's structure and role in protein degradation have highlighted its potential for drug development, especially in PROTAC therapies.
Courtney Pilcher   +6 more
wiley   +1 more source

UniArk:Improving generalisation and consistency for factual knowledge extraction through debiasing [PDF]

open access: yes
Several recent papers have investigated the potential of language models as knowledge bases as well as the existence of severe biases when extracting factual knowledge.
Chen, Pinzhen   +4 more
core   +3 more sources

Kiralnost - ususret 160. obljetnici Pasteurova otkrića [PDF]

open access: yesKemija u Industriji, 2007
The presented review on chirality is dedicated to the centennial birth anniversary of Nobel laureate Vladimir Prelog and 160 years of Pasteur's discovery of chirality on tartrates.
Kojić-Prodić, B., Molčanov, K.
doaj  

Comparative efficacy of pharmacological and non-pharmacological interventions for the acute treatment of adult outpatients with anorexia nervosa: study protocol for the systematic review and network meta-analysis of individual data

open access: yesJournal of Eating Disorders, 2017
Background Outpatient treatment studies of anorexia nervosa (AN) are notoriously hard to conduct given the ambivalence of the patient group and high drop-out rates.
Tracey D. Wade   +6 more
doaj   +1 more source

Simplifying the Design of Knowledge-Based Algorithms Using Knowledge Consistency

open access: yesInformation and Computation, 1995
AbstractProcessor knowledge is an important tool in the study of distributed computer systems. It has led to better understanding of existing algorithms for such systems and to the development of new knowledge-based algorithms. Some of these algorithms use forms of knowledge (e.g., common knowledge) that cannot be achieved in certain systems.
openaire   +2 more sources

Checking a Knowledge-Based System for Consistency and Completeness

open access: yesAi Magazine, 1987
We describe a computer program that implements an algorithm to verify the consistency and completeness of knowledge bases built for the Lockheed expert system (LES) shell. The algorithms described here are not specific to this particular shell and can be applied to many rule-based systems.
Deanne Pecora   +3 more
openaire   +2 more sources

The multiple roles of the NlpC_P60 peptidase family in mycobacteria – an underexplored target for antimicrobial drug discovery

open access: yesFEBS Letters, EarlyView.
The NlpC_P60 superfamily of peptidases is recognised by its key role in bacterial cell wall homeostasis. Recently, studies have also described the involvement of NlpC_P60‐like enzymes in bacterial competitive mechanisms and pathogenesis across several lineages.
Catharina dos Santos Silva   +1 more
wiley   +1 more source

Refining the NaV1.7 pharmacophore of a class of venom‐derived peptide inhibitors via a combination of in silico screening and rational engineering

open access: yesFEBS Letters, EarlyView.
Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma   +8 more
wiley   +1 more source

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