Results 71 to 80 of about 315,857 (305)

Optimizing the computation of overriding

open access: yes, 2015
We introduce optimization techniques for reasoning in DLN---a recently introduced family of nonmonotonic description logics whose characterizing features appear well-suited to model the applicative examples naturally arising in biomedical domains and ...
BC Grau   +17 more
core   +1 more source

Photosynthesis under far‐red light—evolutionary adaptations and bioengineering of light‐harvesting complexes

open access: yesFEBS Letters, EarlyView.
Phototrophs evolved light‐harvesting systems adapted for efficient photon capture in habitats enriched in far‐red radiation. A subset of eukaryotic pigment‐binding proteins can absorb far‐red photons via low‐energy chlorophyll states known as red forms.
Antonello Amelii   +8 more
wiley   +1 more source

The role of fibroblast growth factors in cell and cancer metabolism

open access: yesFEBS Letters, EarlyView.
Fibroblast growth factor (FGF) signaling regulates crucial signaling cascades that promote cell proliferation, survival, and metabolism. Therefore, FGFs and their receptors are often dysregulated in human diseases, including cancer, to sustain proliferation and rewire metabolism.
Jessica Price, Chiara Francavilla
wiley   +1 more source

Using consistency-driven pairwise comparisons in knowledge-based systems [PDF]

open access: yesProceedings of the sixth international conference on Information and knowledge management, 1997
Knowledge acquisition often requires the assessment of qualitative stimuli (e.g., criteria or priorities) such as public safety or the degree of environmental damage. Weights, reflecting the relative importance of the objectives concerned are one of the most commonly used solutions for this kind of data.
Marian Orlowski   +2 more
openaire   +2 more sources

Coherent Integration of Databases by Abductive Logic Programming

open access: yes, 2004
We introduce an abductive method for a coherent integration of independent data-sources. The idea is to compute a list of data-facts that should be inserted to the amalgamated database or retracted from it in order to restore its consistency. This method
Arieli, O.   +3 more
core   +1 more source

The IQ‐compete assay for measuring mitochondrial protein import efficiencies in living yeast cells

open access: yesFEBS Letters, EarlyView.
The efficiency of mitochondrial protein import depends on the properties of the newly synthesized precursor proteins. The Import and de‐Quenching Competition (IQ‐compete) assay is a novel method to monitor the import efficiency of different proteins by fluorescence in living yeast cells.
Yasmin Hoffman   +3 more
wiley   +1 more source

Synthesizing and executing plans in Knowledge and Action Bases [PDF]

open access: yes, 2016
We study plan synthesis for a variant of Knowledge and Action Bases (KABs). KABs have been recently introduced as a rich, dynamic framework where states are full-fledged description logic (DL) knowledge bases (KBs) whose extensional part is manipulated ...
Calvanese, Diego   +3 more
core  

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

open access: yesMolecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes   +20 more
wiley   +1 more source

A set-based reasoner for the description logic $\shdlssx$ (Extended Version)

open access: yes, 2018
We present a \ke-based implementation of a reasoner for a decidable fragment of (stratified) set theory expressing the description logic $\dlssx$ ($\shdlssx$, for short). Our application solves the main TBox and ABox reasoning problems for $\shdlssx$. In
Cantone, Domenico   +2 more
core  

Multi‐omic characterization of consensus molecular subtype 1 (CMS1) colorectal cancer with dampened immune response improves precision medicine

open access: yesMolecular Oncology, EarlyView.
This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti   +10 more
wiley   +1 more source

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