Results 101 to 110 of about 18,050 (261)
FEBS Letters, EarlyView.Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
Simulating properties of the likelihood ratio test for a unit root in an explosive second order autoregression [PDF]
This paper provides a means of accurately simulating explosive autoregressive processes, and uses this method to analyse the distribution of the likelihood ratio test statistic for an explosive second order autoregressive process.
Bent Nielsen, J. James Reade
core
Subset-Guided Consistency Enhancement Assessment Criterion for an Imageset Without Reference
IEEE Access, 2019 In a new era for machine vision, some image enhancement algorithms can be used to improve the quality of an imageset without reference. To assess the performance of imageset enhancement, the existing average criterion utilizes a no-reference image ...
Hao Liu, Dong Wei, Demin Li
doaj +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
A framework for macroeconomic consistency for Zimbabwe [PDF]
The objective of this paper is to apply a framework for macroeconomic consistency to Zimbabwe. Using annual data for 1981and 1987, the paper illustrates the usefulness of imposing consistency on the flow budget accounts (in both current and constant ...
Schmidt-Hebbel, Klaus, Khadr, Ali
core
Solution of the Least Squares Method problem of pairwise comparison matrices [PDF]
, 2008 The aim of the paper is to present a new global optimization method for determining all the optima of the Least Squares Method (LSM) problem of pairwise comparison matrices. Such matrices are used, e.g., in the Analytic Hierarchy Process (AHP).
Bozóki, Sándor
core +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Modeling of Slump Value and Determination of Influental Variables with Regression Approach
Rekayasa Sipil, 2019 There are many factors underlying the instability of the consistency of the concrete mixture. The consistency of the concrete mixture was measured using a slump test. Slump tests are commonly used in measuring the quality of fresh concrete.
Eri Cahyani +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source