Results 131 to 140 of about 18,050 (261)

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Enhancing consistency of AHP-based expert judgements: A new approach and its implementation in an interactive tool

MethodsX
The analytic hierarchy process is an effective method for simplifying complex decision-making processes involving multiple criteria. Experts convey their criteria evaluations through pairwise comparisons that ultimately result in a consistency check of ...
Shimon Frish, Irit Talmor, Omer Hadar, Maxim Shoshany, Aviad Shapira   +4 more
doaj   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Effect of a commercial pectinmethylesterase on tomato paste consistency [PDF]

, 2014
Background: Consistency is one of the main traits that define commercial quality and price of tomato paste. Pectins are partially responsible for consistency in tomato paste, therefore enzymatic pectin modification could be used to increase paste ...
Z\ufa\uf1iga-Hansen, Mar\ueda Elvira, P\ue9rez-Torres, Eduardo, Caballero-Vald\ue9s, Eduardo, Fern\ue1ndez-Parodi, Jos\ue9   +3 more
core  

Note on consistency ratio: a reply

Mathematical and Computer Modelling, 2002
Apostolou, B., Hassell, J. M.
openaire   +2 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Consistency Issues in the Construction of Annual and Quarterly Productivity Indices [PDF]

International Productivity Monitor, 2019
Productivity change is generally measured in index form as ratio of output quantity index over input quantity index. Several statistical agencies publish quarterly as well as annual productivity indices, constructed from what appear to be basically the ...
Bert M. Balks
doaj  

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Penalized Exponentially Tilted Likelihood for Growing Dimensional Models with Missing Data

Entropy
This paper develops a penalized exponentially tilted (ET) likelihood to simultaneously estimate unknown parameters and select variables for growing dimensional models with missing response at random.
Xiaoming Sha, Puying Zhao, Niansheng Tang   +2 more
doaj   +1 more source

Bias and consistency of the maximum Sharpe ratio [PDF]

The Journal of Risk, 2005
openaire   +1 more source