Results 91 to 100 of about 304,397 (263)

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

open access: yesFEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo   +7 more
wiley   +1 more source

Contribuição ao estudo de propriedades do solo-cimento autoadensável para fabricação de paredes monolíticas

open access: yesAmbiente Construído
Resumo Foram estudadas as propriedades físico-mecânicas do solo-cimento autoadensável (SCAA), de forma a desenvolver misturas de solo, cimento, água e aditivos para o alcance de desempenho mínimo para sua aplicação em fôrmas monolíticas sem a necessidade
Ana Paula da Silva Milani   +1 more
doaj   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

Percepção sonora e conforto acústico em espaços urbanos do município de Belo Horizonte, MG

open access: yesAmbiente Construído
Resumo O presente artigo tem como objetivo apresentar e analisar as respostas dos usuários de espaços urbanos abertos com relação à percepção do volume sonoro e à avaliação de conforto acústico, com base em dados coletados em campo durante o ano de 2013,
Simone Queiroz da Silveira Hirashima   +1 more
doaj   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

open access: yesFEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin   +3 more
wiley   +1 more source

The consistency strength of projective uniformization, revisited

open access: yes, 1997
It is shown that if every projective set of reals is Lebesgue measurable and has the property of Baire, if every projective set in the plane has a projective uniformization, and if Steel's K exists, then J^K_{ω_1} \models "there are infinitely many strong cardinals." This is best possible, by a recent result of Steel.
openaire   +2 more sources

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

open access: yesFEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose   +9 more
wiley   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

open access: yesAging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang   +3 more
wiley   +1 more source

Impact of Hand Grip and Shoulder Muscle Strengthening Programme on Performance in Air Rifle Shooters

open access: yesInternational Journal of Physiotherapy
Background: Air rifle shooting is a precision sport requiring stability, muscle endurance, and fine motor control. Hand grip strength and shoulder muscle stability are critical for accuracy and consistency.
Revanth Gowda M C, Purusotham Chippala
doaj   +1 more source

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