Results 81 to 90 of about 304,397 (263)

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

FEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa, Kazuhiko Higashida, Naoya Nakai   +2 more
wiley   +1 more source

Effects of using chemical admixture with nanosilica in the consistency and mechanical strength of concrete

Revista IBRACON de Estruturas e Materiais, 2019
The concrete’s performance depends on its behavior in the fresh and hardened states, since the workability corroborates for the transport and application processes of the material, while the mechanical strength guarantees structural effectiveness and ...
T. F. CAMPOS NETO, A. L. B. GEYER
doaj   +2 more sources

Parsimony in landscape metrics: Strength, universality, and consistency

Ecological Indicators, 2008
Ecologists can be overwhelmed by the number of metrics available to quantify landscape structure. Clarification of interrelationships and redundancy is needed to guide metric selection and interpretation for the purpose of landscape monitoring. In this study we identified independent components of class- and landscape-level structure in multiple ...
Samuel A. Cushman, Kevin McGarigal, Maile C. Neel   +2 more
openaire   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

FEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee, Ga Seul Lee, JinHan Kim, Kwang‐Hyun Park, Seong‐Ryung Go, Jeong Hee Moon, Eui‐Jeon Woo   +6 more
wiley   +1 more source

Strength, Sulfate Resistance, and Microstructural Characteristics of Concrete With Partial Cement Replacement Using Eggshell Powder and Wheat Straw Ash

Advances in Materials Science and Engineering
This study explores the partial replacement of ordinary Portland cement (OPC) with a composite of eggshell powder (ESP) and wheat straw ash (WSA) in C-25 concrete, focusing on mechanical performance and durability.
Abdulsemad Jemal Jema, Fikreyesus Demeke Cherkos   +1 more
doaj   +1 more source

Application of industrial by-products as mineral admixtures for self-compacting concrete

Građevinar, 2018
Although the use of waste materials as mineral admixtures for self-compacting concrete can contribute to solving the problem of their disposal, the effect of such use should be further explored.
Saša Marinković, Milan Protić, Stepa Paunović, Ivan Nešović, Jelena Bijeljić   +4 more
doaj   +1 more source

Why human connection is the true metric of research success

FEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan, Mattias Wei Ren Kon, Xavier Coumoul, Fun Man Fung   +3 more
wiley   +1 more source

Merging Interstage Fractionation and Low Consistency Advantages During the TMP Refining Process: Part III – How Fibre Morphology Impacts Paper Properties

BioResources, 2014
Fibre morphology and its evolution during refining and fractionation at low consistency were studied to understand the key relationships between the mechanical properties of paper and those of fibres.
My-Mustapha Lemrini, Robert Lanouette, Gaston Michaud   +2 more
doaj   +1 more source