Results 171 to 180 of about 2,971,508 (208)

Revitalization in Traumatized Immature Teeth With External Inflammatory Root Resorption: A Systematic Review

open access: yesDental Traumatology, EarlyView.
ABSTRACT Introduction This study aimed to evaluate whether revitalization can be indicated in the treatment of traumatized immature teeth with external inflammatory root resorption (EIRR). Methods The protocol of the review was developed in accordance with the PRISMA checklist and registered in the PROSPERO database (CRD42023446609).
Ghina Al Khourdaji   +4 more
wiley   +1 more source

Iloperidone treatment mitigates the Juvenile Huntington's Disease phenotype possibly via Sigma‐1 Receptor Modulation

open access: yesThe FEBS Journal, EarlyView.
We investigated the potential of iloperidone as an activator of Sigma‐1 receptor (S1R) neuroprotective function in juvenile Huntington's disease (jHD). We tested iloperidone on cortical neurons differentiated from patient‐derived iPSCs, demonstrating that it acts as a S1R agonist, decreasing apoptosis, huntingtin aggregation, and oxidative stress ...
Ersilia Fornetti   +11 more
wiley   +1 more source

High‐Fat Diet Reprograms the Periapical Immune Landscape in a Mouse Model of Apical Periodontitis: A Spatial Transcriptomics Study

open access: yesInternational Endodontic Journal, EarlyView.
ABSTRACT Introduction Apical periodontitis (AP) is an inflammatory disease of the periapical tissues driven by host responses to endodontic infection, and systemic metabolic disturbances, such as high‐fat diet (HFD)–induced dysmetabolism, may exacerbate tissue destruction. This study aimed to determine how chronic HFD exposure alters periapical myeloid
Maryam Ghaffari   +3 more
wiley   +1 more source

Preserved B Cell Function in CD23‐Cre Transgenic Mice Allows Reliable Flox‐Only Controls in Mouse Models

open access: yesImmunology, EarlyView.
Expression of CD23‐Cre does not impair the function of mature B cells or the establishment of the humoral immune response. Therefore, Flox‐only mice are suitable controls in studies using a CD23‐Cre mouse model. This reduces the number of surplus animals generated and supports the 3Rs principle in animal research.
Leonie Steinmetzer   +12 more
wiley   +1 more source

The application of machine learning models to optimal TSP tour length estimation

open access: yesInternational Transactions in Operational Research, EarlyView.
Abstract The traveling salesman problem (TSP) is a well‐known NP‐hard problem in combinatorial optimization, with numerous applications in logistics and elsewhere. This paper introduces a machine learning‐based approach to estimate the optimal tour length of the TSP, using linear regression, random forests (RF), and neural networks, including ...
Shuhan Kou, Bruce Golden, Luca Bertazzi
wiley   +1 more source

Comparison of volume- and surface-based magnetic resonance imaging morphometry algorithms in the detection of focal cortical dysplasia. [PDF]

open access: yesEpilepsia
Bücheler L   +17 more
europepmc   +1 more source

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