Results 41 to 50 of about 2,971,508 (208)

On composition of signed graphs [PDF]

, 2012
A graph whose edges are labeled either as positive or negative is called a signed graph. In this article, we extend the notion of composition of (unsigned) graphs (also called lexicographic product) to signed graphs.
Shahul Hameed, K., Germina, K.
core   +1 more source

Transient Sleep Deprivation Induces Persistent Auditory Neuropathy via ROS‐Initiated Neuroinflammation and BK Channel Suppression

Advanced Science, EarlyView.
Sleep disturbance severity closely tracks hearing loss in a clinical cohort, yet the mechanistic link remains unclear. Acute sleep deprivation is shown to trigger transient cochlear oxidative stress that switches into a self‐sustaining neuroinflammatory state, suppressing BK channels and causing irreversible synaptopathy.
Dan Chen, Ying Ma, Lixuan Huang, Xin Chen, Fanliang Kong, Zhenzhou Qian, Mingyue Guan, Xinlin Wang, Yanyan Yang, Shasha Zhang, Peng Li, Renjie Chai   +11 more
wiley   +1 more source

The n-th Power Signed Graphs-II [PDF]

, 2010
For standard terminology and notion in graph theory we refer the reader to Harary [6]; the non-standard will be given in this paper as and when required.
Reddyy, P. Siva Kota, Vijay, S., Lokeshaz, V.   +2 more
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Molecular Glue Degraders Enhance CAPRIN1‐Dependent Lysosomal Degradation of APP and Reduce Amyloid β in Alzheimer's Disease

Advanced Science, EarlyView.
A new class of lysosome‐directed molecular glue degraders selectively enhance CAPRIN1–APP interactions, driving APP degradation and reducing amyloid‐β production in human neurons and Alzheimer's disease mouse models. This CAPRIN1‐dependent targeted protein degradation strategy reveals a previously unrecognized therapeutic approach for disrupting the ...
Sunghan Jung, Xu Wang, Bin Liu, Raktim Roy, Nancy Jaiswal, Ratan K. Rai, Yuichiro Takagi, Cen Gao, Lifan Zeng, Ho‐Yin Lo, Reagan K. Wohlford, Ryan K. Higgins, Bruce T. Lamb, Anantha Shekhar, Anita C. Bellail, Chunhai Hao   +15 more
wiley   +1 more source

Crown reductions for the Minimum Weighted Vertex Cover problem [PDF]

, 2004
The paper studies crown reductions for the Minimum Weighted Vertex Cover problem introduced recently in the unweighted case by Fellows et al. [Blow-Ups, Win/Win's and crown rules: some new directions in FPT, in: Proceedings of the 29th International ...
Chlebikova, Janka, Miroslav Chlebík, Chlebik, M., Miroslav Chlebik (4461319), Janka Chlebíková, Janka Chlebíková (16060964)   +5 more
core   +1 more source

Complexity of planar signed graph homomorphisms to cycles

, 2020
International audienceWe study homomorphism problems of signed graphs from a computational point of view. A signed graph is an undirected graph where each edge is given a sign, positive or negative. An important concept when studying signed graphs is the
Mitsou, Valia, Foucaud, Florent, Dross, François, Pierron, Théo, Ochem, Pascal   +4 more
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A Note on Path Signed Digraphs [PDF]

, 2010
The concept of a line signed digraph is generalized to that of a path signed ...
S. Vijay, H. C. Savithri, P. Siva Kota Reddy, Savithri, H. C., Reddyy, P. Siva Kota, Vijayz, S.   +5 more
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Temporal Trajectories of the Tau Aggregate Interactome Reveal Stage‐Specific Vulnerabilities in Alzheimer's Disease

Advanced Science, EarlyView.
Tau populations with different aggregation states associate with distinct sets of proteins in the Alzheimer's disease brain. Proteomic discovery combined with single‐molecule analysis in neurons reveals dynamic associations involving proteostasis, metabolism and RNA biology.
Dorothea Böken, Paula Beltran Lobo, Yunzhao Wu, Lyla A. Rowe, Emre Fertan, Cara L. Croft, Maria Jimenez‐Sanchez, Dezerae Cox, David Klenerman   +8 more
wiley   +1 more source

AI‐Designed TREM1‐Targeted LYTAC Nanoparticles Reprogram the Neuroimmune Microenvironment in Traumatic Brain Injury

Advanced Science, EarlyView.
AI‐enabled de novo design of a TREM1 binder, integrated into a BBB‐crossing and macrophage‐targeted nanoplatform, enables TREM1 degradation and attenuates neuroinflammation, thereby promoting neuroprotection and tissue repair after traumatic brain injury. ABSTRACT Secondary neuroinflammation drives progressive damage after traumatic brain injury (TBI),
Yimin Huang, Yuan Liu, Huan Peng, Yu Ni, Zhengqiao Jiang, Chenxuan Yu, Xincheng Zhang, Huayu Kang, Yanchao Liu, Juan Chen, Kai Zhao, Lin Han, Xin Zou, Kai Shu, Xiaochuan Wang, Jian‐Zhi Wang, Ting Lei, Chao Gan, Jianfeng Liu, Huaqiu Zhang   +19 more
wiley   +1 more source

Connected signed graphs L-cospectral to signed ∞-graphs

, 2019
A signed graph is a pair (G,sigma), where G is a graph and sigma is the sign function on the edges of G. For a signed graph we consider the Laplacian matrix defined as L=D-A, where D is the matrix of vertex degrees of G and A the (signed) adjacency ...
Brunetti, Maurizio, Belardo, Francesco
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