Results 51 to 60 of about 2,971,508 (208)

Single‐Nucleus Transcriptomic Atlas of Human Vellus Hair Pilosebaceous Units Reveals Age‐Associated Remodeling

open access: yesAdvanced Science, EarlyView.
Human vellus pilosebaceous units (PSUs) remain uncharted. This single‐nucleus atlas reveals coordinated remodeling of the aging PSU niche: reduced bulge stem cell representation with altered regenerative programs, increased representation of a stress‐responsive channel+ epithelial state, enhanced androgen‐responsive sebaceous programs, reduced ...
Ya'nan Li   +9 more
wiley   +1 more source

Synergistic Mechano‐Fluidic Self‐Fusion of Poly(Vinyl Alcohol)‐Modified Liquid‐Metal Particles for Post‐Treatment‐Free Soft Electronics

open access: yesAdvanced Science, EarlyView.
Poly(vinyl alcohol)‐modified liquid‐metal particles form conductive networks through spray‐induced self‐fusion without additional post‐treatment. Spray impact initiates oxide‐shell rupture and electrical contact, while subsequent Marangoni flow and capillary forces promote particle redistribution, neck growth, and network consolidation. This sequential
Keun‐Young Yook   +13 more
wiley   +1 more source

Oral Astilbin Nanogels Modulate Senescence‐Associated CD4+ T Cells and Promote Treg Induction in Aged Mice with Colitis

open access: yesAdvanced Science, EarlyView.
Fluorinated β‐glucan/pectin nanogels enable colon‐targeted oral delivery of astilbin through gastrointestinal protection, β‐glucanase‐responsive release, mucus penetration, and prolonged retention. The released astilbin attenuates senescence‐associated features of CD4+ T cells and promotes Treg responses, while the nanogel matrix modulates the gut ...
Lei Zhao   +11 more
wiley   +1 more source

Signed star (k,k)-domatic number of a graph [PDF]

open access: yes, 2014
Let \(G\) be a simple graph without isolated vertices with vertex set \(V(G)\) and edge set \(E(G)\) and let \(k\) be a positive integer. A function \(f:E(G)\longrightarrow \{-1, 1\}\) is said to be a signed star \(k\)-dominating function on \(G\) if ...
Volkmann, L.   +5 more
core   +3 more sources

An Integrated Artificial Intelligence Framework for Nanomedicine Engineering

open access: yesAdvanced Science, EarlyView.
This review outlines a closed‐loop AI ecosystem for nanomedicine engineering. By synergizing multimodal data harmonization, objective‐driven AI architectures, and automated high‐throughput validation, this “Design‐Make‐Test‐Analyze” (DMTA) workflow transforms traditional heuristic formulation into a predictive, self‐optimizing paradigm, accelerating ...
Meichen Dong   +10 more
wiley   +1 more source

Interlacing Properties of Eigenvalues of Laplacian and Net-Laplacian Matrix of Signed Graphs [PDF]

open access: yes, 2023
This paper explores interlacing inequalities in the Laplacian spectrum of signed cycles and investigates interlacing relationship between the spectrum of the net-Laplacian of a signed graph and its subgraph formed by removing a vertex together with its ...
Guragain, Satyam, Srivastava, Ravi
core  

Enhancing Specific Stiffness of Nano‐Architected Materials Through Generative AI and Active Learning

open access: yesAdvanced Science, EarlyView.
A structure‐centric generative framework searches voxelated design space directly, coupling a variational autoencoder with multi‐objective optimization and active learning to progressively expand the validated design domain. The discovered nano‐architectures, realized as pyrolytic carbon by two‐photon lithography, deliver 18–23% higher stiffness and 26–
Jinwook Yeo   +4 more
wiley   +1 more source

Decomposition of a signed graph into strongly connected components and its signed poset structure

open access: yes, 1994
A signed graph (or a bidirected graph) is a graph whose each arc has either two positive end-vertices (tails), two negative end-vertices (heads), or one positive end-vertex (a tail) and one negative end vertex (a head).
Ando, K.   +3 more
core  

Engineering a Bioelectronic Hybrid Heart with Integrated Sensing and Electrical Modulation

open access: yesAdvanced Science, EarlyView.
A bioelectronic hybrid heart is engineered by integrating iPSC‐derived cardiomyocytes, a decellularized cardiac scaffold, a cell‐laden ECM coating, and a flexible electronic mesh. The embedded electrodes enable real‐time recording of spontaneous electrical activity and localized stimulation, allowing controlled pacing and modulation of activation ...
Itai Cabilly   +7 more
wiley   +1 more source

Steric‐Pressure‐Driven Topological Reconstruction for High‐Performance Zintl Phase Thermoelectrics with Machine‐Learning Validation

open access: yesAdvanced Science, EarlyView.
Synergistic Sr and Ag co‐doping drives steric‐pressure‐induced reconstruction from a 2D layered structure to a cross‐linked 3D framework in the Ca9‐xSrxZn4+y‐zAgzSb9 system, enhancing carrier mobility while maintaining a large Seebeck coefficient and doubling ZT to 0.73 at 873 K, with hybrid transfer machine learning further capturing the compositional
Siyeon Kim   +7 more
wiley   +1 more source

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