Results 101 to 110 of about 1,008,987 (263)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Enhancing Urban Flood Susceptibility Assessment by Capturing the Features of the Urban Environment

Remote Sensing
The frequent occurrence of urban floods (UFs) poses significant threats to public safety and the national economy. Accurate estimation of urban flood susceptibility (UFS) and the identification of potential hotspots are critical for effective UF ...
Juwei Tian, Yinyin Chen, Linhan Yang, Dandan Li, Luo Liu, Jiufeng Li, Xianzhe Tang   +6 more
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Research on Hyperspectral Inversion of Soil Organic Carbon in Agricultural Fields of the Southern Shaanxi Mountain Area

Remote Sensing
Rapidly obtaining information on the content and spatial distribution of soil organic carbon (SOC) in farmland is crucial for evaluating regional soil quality, land degradation, and crop yield.
Yunhao Han, Bin Wang, Jingyi Yang, Fang Yin, Linsen He   +4 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Ecological Risk Assessment and Source Analysis of Heavy Metals in Farmland Soil in Yangchun City Based on APCS-MLR and Geostatistics

Agriculture
Yangchun City, a typical polymetallic ore distribution area in Guangdong Province (China), was selected as the research region to study the content, distribution, source, and possible impacts of heavy metals (HMs) (Arsenic: As; Cadmium: Cd; Chromium: Cr;
Yingyuting Li, Yili Zhang, Junyu Chen, Guangfei Yang, Haihui Li, Jinjin Wang, Wenyan Li   +6 more
doaj   +1 more source

European Airline Mergers, Alliance Consolidation, and Consumer Welfare [PDF]

This paper explores the effects of a European airline merger followed by a consolidation of two competing international alliances. The exercise has been inspired by the Air France-KLM merger, which is expected to spur consolidation of the Northwest-KLM ...
Eric Pels, Jan K. Brueckner
core  

Unsupervised String Transformation Learning for Entity Consolidation

, 2018
Data integration has been a long-standing challenge in data management with many applications. A key step in data integration is entity consolidation. It takes a collection of clusters of duplicate records as input and produces a single "golden record ...
Abedjan, Ziawasch, Deng, Dong, Elmagarmid, Ahmed, Ilyas, Ihab F., Li, Guoliang, Madden, Samuel, Ouzzani, Mourad, Stonebraker, Michael, Tang, Nan, Tao, Wenbo   +9 more
core   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Large-scale and rapid perception of regional economic resilience from data-driven insights

International Journal of Digital Earth
Developing general resilience measures that take into account spatio-temporal dynamics to withstand the adverse effects of shocks on the economy is urgent during the COVID-19 pandemic. However, rapid perception of city economic resilience at large scales
Tong Cheng, Le Ma, Yonghua Zhao, Chunjiang Zhao   +3 more
doaj   +1 more source