Results 111 to 120 of about 451,727 (304)

Spatio-temporal interaction and constraint effects between ecosystem services and human activity intensity in Shaanxi Province,China

open access: yesEcological Indicators
Identifying spatial heterogeneity in ecosystem services and understanding the spatial and temporal correlations between ecosystem service exploration and human activity intensity are vital for achieving regional harmony between human activities and the ...
Qimin An   +5 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Enhancing Urban Flood Susceptibility Assessment by Capturing the Features of the Urban Environment

open access: yesRemote Sensing
The frequent occurrence of urban floods (UFs) poses significant threats to public safety and the national economy. Accurate estimation of urban flood susceptibility (UFS) and the identification of potential hotspots are critical for effective UF ...
Juwei Tian   +6 more
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

The Effects of School Board Consolidation and Financing on Student Performance [PDF]

open access: yes
Over the last 20 years, states and provinces have become increasingly involved in the financing and administration of elementary and secondary education.
A. Abigail Payne, Steve Chan, John Leach
core  

Catalogue of analytical solutions for consolidation of unsaturated soils subjected to various initial conditions and time-dependent loadings [PDF]

open access: yes, 2016
University of Technology Sydney. Faculty of Engineering and Information Technology.Soil consolidation has been a primary geotechnical interest for decades.
Ho, Huu Liem
core  

Ecological Risk Assessment and Source Analysis of Heavy Metals in Farmland Soil in Yangchun City Based on APCS-MLR and Geostatistics

open access: yesAgriculture
Yangchun City, a typical polymetallic ore distribution area in Guangdong Province (China), was selected as the research region to study the content, distribution, source, and possible impacts of heavy metals (HMs) (Arsenic: As; Cadmium: Cd; Chromium: Cr;
Yingyuting Li   +6 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

"Effects of Bank Consolidation Promotion Policy: Evaluating the Bank Law in 1927 Japan" [PDF]

open access: yes
This paper investigates the impact of bank consolidations promoted by government policy, using data from prewar Japan, when the financial authorities promoted them by dint of the Bank Law in 1927.
Michiru Sawada, Tetsuji Okazaki
core  

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

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