Results 111 to 120 of about 451,727 (304)
Identifying spatial heterogeneity in ecosystem services and understanding the spatial and temporal correlations between ecosystem service exploration and human activity intensity are vital for achieving regional harmony between human activities and the ...
Qimin An +5 more
doaj +1 more source
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Enhancing Urban Flood Susceptibility Assessment by Capturing the Features of the Urban Environment
The frequent occurrence of urban floods (UFs) poses significant threats to public safety and the national economy. Accurate estimation of urban flood susceptibility (UFS) and the identification of potential hotspots are critical for effective UF ...
Juwei Tian +6 more
doaj +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
The Effects of School Board Consolidation and Financing on Student Performance [PDF]
Over the last 20 years, states and provinces have become increasingly involved in the financing and administration of elementary and secondary education.
A. Abigail Payne, Steve Chan, John Leach
core
Catalogue of analytical solutions for consolidation of unsaturated soils subjected to various initial conditions and time-dependent loadings [PDF]
University of Technology Sydney. Faculty of Engineering and Information Technology.Soil consolidation has been a primary geotechnical interest for decades.
Ho, Huu Liem
core
Yangchun City, a typical polymetallic ore distribution area in Guangdong Province (China), was selected as the research region to study the content, distribution, source, and possible impacts of heavy metals (HMs) (Arsenic: As; Cadmium: Cd; Chromium: Cr;
Yingyuting Li +6 more
doaj +1 more source
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
"Effects of Bank Consolidation Promotion Policy: Evaluating the Bank Law in 1927 Japan" [PDF]
This paper investigates the impact of bank consolidations promoted by government policy, using data from prewar Japan, when the financial authorities promoted them by dint of the Bank Law in 1927.
Michiru Sawada, Tetsuji Okazaki
core
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source

