Results 171 to 180 of about 365,733 (318)

Deregulation, Consolidation, and Efficiency: Evidence From the Spanish Insurance Industry [PDF]

open access: yes
This paper provides new information on the effects of deregulation and consolidation in financial services markets by analyzing the Spanish insurance industry.
J. David Cummins, Maria Rubio-Misas
core  

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

Fiscal consolidation strategy : [Version 21 September 2012]

open access: yes, 2012
In the aftermath of the global financial crisis and great recession, many countries face substantial deficits and growing debts. In the United States, federal government outlays as a ratio to GDP rose substantially from about 19.5 percent before the ...
Cogan, John F.   +3 more
core  

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Horizontal Consolidation in the U.S. Food Processing Industry: Boon or Bane?

open access: yes
This study measured the effect of increased concentration on industry market power and cost efficiency, using a bilateral oligopoly model. Cost efficiency gains dominate market power effects from increase in industry concentration.
Tostao, Emilio, Chung, Chanjin
core  

Correction: Evaluation of different machine learning models and novel deep learning-based algorithm for landslide susceptibility mapping

open access: yesGeoscience Letters, 2023
Tingyu Zhang   +8 more
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

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