Results 191 to 200 of about 365,733 (318)

Consolidation as a Regulatory Compliance Strategy: Small Drinking Water Systems and the Safe Drinking Water Act

Despite extensive research and policy initiatives to increase the technical, financial, and managerial capacity of small drinking water systems, there has been little research focusing on understanding how consolidation can increase the overall capacity ...
Braden, John B., Lee, Min-Yang A.
core  

3D-Printed Patient-Specific Guides Versus Conventional Techniques for Scaphoid Reconstruction: A Comparative Study of 89 Cases. [PDF]

J Orthop Res
Mania S, Maniglio M, Wirth MA, Nagy L, Reissner L, Schweizer A.   +5 more
europepmc   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

AN ANALYSIS OF BANK CONSOLIDATION TRENDS IN RURAL PENNSYLVANIA

U.S. banking markets have undergone important structural and institutional changes. Overall, the sector has experienced steady consolidation through mergers and acquisitions that have resulted in fewer banks holding a greater value of the total assets ...
Stokes, Jeffrey R., Bae, Jeong Hwan, Shields, Martin   +2 more
core  

Neutrophil-to-lymphocyte ratio mediates pulmonary consolidation through oxidative stress in children with <i>Mycoplasma pneumoniae</i> pneumonia. [PDF]

Ann Med
Zhao J, Wang Z, Wang Y, Dai Q, Qu S, Ru L.   +5 more
europepmc   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Fixed-duration cytarabine consolidation improves relapse-free survival over indefinite AZA-VEN in younger AML. [PDF]

Blood Cancer J
Swain RN, Jain A, Wadhera S, Singh C, Jandial A, Khadwal A, Sachdeva MU, Naseem S, Malhotra P, Prakash G.   +9 more
europepmc   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Post-Learning Offline Pauses Support Consolidation Beyond the Mind-Wandering State. [PDF]

Clocks Sleep
Costa Dias J, Peigneux P.
europepmc   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source