Results 101 to 110 of about 2,853,808 (283)

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

WAUSAU METROPOLITAN COOPERATION, COLLABORATION AND CONSOLIDATION [PDF]

open access: yes, 2012
A Field Project Submitted In Partial Fulfillment of the Requirements For the Degree of Master of Public ...
Herbert, William D
core  

Mode Classification of Rural Residential Land Consolidation Based on Support Degree

open access: yesShuitu baochi yanjiu, 2013
For the purpose of studying the arrangement types and development directions of rural residential land,which is in different environment of land plan and own conditions,taking Feixiang County as an case,according to the principle of external‘spillover ...
TIAN Zhen-sheng   +3 more
doaj  

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Land Consolidation Potential and Spatial Restructuring of Hollowed Village in the Loess Hilly and Gully Region

open access: yesShuitu baochi yanjiu, 2020
In order to understand the rural population hollowing level and the potential of land consolidation in the loess hilly and gully region, Changwu County of Shaanxi Province was taken as an example, which is located in the loess hilly and gully region.
GE Chenxi   +4 more
doaj  

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

Study on evaluation method for soil sample disturbance based on normalized shear modulus

open access: yesYantu gongcheng xuebao
Among various existing methods for evaluating soil sampling disturbance, only the modified volumetric compression method can independently reflect the influence of soil structural damage on the degree of sampling disturbance, while the disturbance ...
CHEN Yun 1, 2, LUO Minmin 1, 2, ZHOU Yanguo 3, TIAN Yu 3
doaj   +1 more source

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

Banking industry's consolidation: what's a small business to do? [PDF]

open access: yes
Relaxation of the rules governing where banks can expand and new technologies for providing banking services have contributed to rapid consolidation in the industry. In addition, the number of commercial banks in the United States has been shrinking, and
Loretta J. Mester
core  

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

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