Results 191 to 200 of about 18,458 (301)

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Lung Ultrasound Findings in Pediatric Mycoplasma Pneumoniae Pneumonia: A Prospective Multicenter Pilot Study. [PDF]

open access: yesChildren (Basel)
Francavilla M   +17 more
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

The Role of CEUS in the Diagnosis and Follow-Up of Pleuropulmonary Diseases and Interventional Procedures. [PDF]

open access: yesJ Clin Med
Boccatonda A   +9 more
europepmc   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

Characteristics of successful fiscal consolidations

open access: yes
This bachelor's thesis focuses on fiscal consolidations and the identification of characteristics that contribute to its successful implementation. The aim of the thesis is to identify factors that led to successful fiscal consolidation in selected ...
CÁBOVÁ, Tereza
core  

All consolidations are not infective: Look beyond ARDS

open access: yesJournal of Emergencies, Trauma and Shock, 2019
Mohammed Ismail Nizami   +2 more
doaj   +1 more source

Autoimmune-Associated Pulmonary Inflammatory Myofibroblastic Tumour: A Diagnostic and Therapeutic Challenge. [PDF]

open access: yesRespirol Case Rep
Hau NB   +7 more
europepmc   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

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