Results 31 to 40 of about 18,458 (301)

Neuronal polarity: consolidation for growth, growth for consolidation [PDF]

The EMBO Journal, 2009
EMBO J 28, 248–260 (2009); published online 4 February 2009 [PMC free article] [PubMed] Axonal elongation involves the coordinated assembly and activation of molecular pathways in response to environmental signals. Neurons sense the environment at growth cones to decide on further growth, arborization or consolidation.
Gärtner, Annette, Dotti, Carlos G
openaire   +2 more sources

EXCESSIVE DEFICIT PROCEDURE IN VISEGRAD COUNTRIES

RUDN Journal of Economics, 2018
The authors state that the fiscal policies conducted by EU member states have their limits since there are supranational rules and norms. The Excessive Deficit Procedure (EDP) seems to be a topical issue, because it binds member states with budget ...
J N Komissarova, E A Sergeev
doaj   +1 more source

Clinical and Biological Features of Response in Resistant Neuroblastoma to 131I‐Metaiodobenzylguanidine Radiotherapy in the Anti‐GD2 Immunotherapy Era

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background 131I‐metaiodobenzylguanidine (131I‐MIBG) radiotherapy is a key treatment for relapsed and refractory (R/R) neuroblastoma (NB). Patients with R/R disease treated in the modern era are increasingly exposed to anti‐GD2 immunotherapy, which exerts selective pressure and may modify both tumor cell state and microenvironment.
Benjamin J. Lerman, Katherine K. Matthay, Fabienne Hollinger, Catriona Black, Ann A. Lazar, Miguel Pampaloni, Steven G. DuBois, Kieuhoa T. Vo   +7 more
wiley   +1 more source

Faut-il réinsérer les tubérosités dans les prothèses inversées d’épaule sur fracture ?

La Revue Marocaine de Chirurgie Orthopédique et Traumatologique (RMACOT)
Hypothèse :  Evaluer l’intérêt de la consolidation des tubérosités lors de la mise en place de prothèse inversée de l’épaule pour des fractures de l’extrémité proximale de l’humérus sur les mobilités rotationnelles et comparer nos résultats à la ...
Yasser Sbihi, Oussama Eladaoui, Med Amine Choukri, Amine Roujdi , Yassir El Andaloussi , Ahmed Reda Haddoun, driss Bennouna, C Templaera, Mustapha Fadili   +8 more
doaj   +1 more source

Deep Sequencing of FLT3‐ITD Enables Response Evaluation and Post‐Treatment Monitoring in Childhood AML: An Exploratory Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background An internal tandem duplication in the gene encoding Fms‐like tyrosine kinase 3 (FLT3‐ITD) is associated with high relapse risk and poor prognosis in acute myeloid leukemia (AML) and plays a crucial role in treatment decisions. Measurable residual disease (MRD) analysis of FLT3‐ITD during and after treatment has shown prognostic ...
Sofie Johansson Alm, Bea Tornberg, Erik Delsing Malmberg, Henrik Hasle, Kristian Løvvik Juul‐Dam, Lars Palmqvist, Borhan R. Saeed, Giti Shah Barkhordar, Anastasia Soboli, Anna Staffas, Jonas Abrahamsson, Linda Fogelstrand   +11 more
wiley   +1 more source

Point-of-care lung ultrasound for diagnosis of Pneumocystis jirovecii pneumonia: notes from the field

Critical Ultrasound Journal, 2018
Background Thoracic ultrasound is helpful to evaluate lung pathology in patients with acute dyspnea. Several studies have demonstrated the efficacy of point-of-care ultrasound in patients with extrapulmonary TB and HIV co-infection.
Maria Teresa Giordani, Francesca Tamarozzi, Daniel Kaminstein, Enrico Brunetti, Tom Heller   +4 more
doaj   +1 more source

Claudin‐6 Protein Expression in Atypical Teratoid/Rhabdoid Tumors Is Strongly Enriched in the Molecular Subgroup AT/RT‐TYR

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Claudin‐6 has emerged as a promising immunotherapeutic target, yet protein‐level data in atypical teratoid/rhabdoid tumors (AT/RTs) have been inconsistent. We analyzed 36 well‐characterized AT/RT samples and found membranous claudin‐6 protein expression in 58% of cases, with striking enrichment in the molecular subgroup AT/RT‐TYR (100%) and ...
Victoria E. Fincke, Christian Thomas, Michael C. Frühwald, Pascal D. Johann, Martin Hasselblatt   +4 more
wiley   +1 more source

Time Toxicity in Wilms Tumor: Quantifying the Burden of Healthcare Interaction in the First Year After Diagnosis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Wilms tumor (WT) treatment imposes a significant time burden on patients and their families. Time toxicity is a patient‐centered metric that quantifies the burden of healthcare interaction. We sought to define time toxicity in the first year after diagnosis of WT and hypothesized that it would increase as tumor stage and treatment ...
Caleb Q. Ashbrook, Veerain Gupta, Nicholas J. Clark, Vijay Rings, Lauren E. Corona, Douglass B. Clayton, Daniel J. Benedetti   +6 more
wiley   +1 more source

Uncertain fiscal consolidations [PDF]

, 2012
The paper explores the macroeconomic consequences of fiscal consolidations whose timing and composition are uncertain. Drawing on the evidence in Alesina and Ardagna (2010), we emphasize whether or not the fiscal consolidation is driven by tax rises or ...
Huixin Bi, Campbell Leith, Leeper, Eric M., Leith, C., Leith, Campbell, Bi, Huixin, Leeper, E.M., Leith, C.B., Eric M. Leeper, Bi, H.   +9 more
core   +1 more source

The Role of Hematopoietic Cell Transplantation in Ataxia‐Telangiectasia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Ataxia‐telangiectasia (A‐T) is a DNA repair disorder characterized by neurodegeneration, immunodeficiency, and cancer predisposition. Hematopoietic cell transplantation (HCT) is an established therapy in related disorders such as Fanconi anemia (FA) and Nijmegen breakage syndrome (NBS), but its role in A‐T is unclear.
Laila Alkhouli, Seth Rotz, Masatoshi Takagi, Richa Sharma   +3 more
wiley   +1 more source