Results 131 to 140 of about 20,991 (253)
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
This note aims to establish the nature of the consonant cluster -rdh- the character of which has not been commented on to my knowledge in modern scholarship.(1) Before dealing with the matter at hand it will be convenient to recapitulate the relevant ...
Ó Riain, Gordon +1 more
core
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Analyzing the Pattern of L1 Sounds on L2 Sounds Produced by Javanese Students of Stkip PGRI Jombang
The studyconcerns on an analysis on the tendency of first language (L1) sound patterning on second language (L2) sounds done by Javanese students.Focusing on the consonant sounds, the data were collected by recording students’ pronunciationof English ...
Daning Hentasmaka
doaj
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Predicting Consonant Duration with Bayesian Belief Networks [PDF]
Consonant duration is influenced by a number of linguistic factors such as the consonant s identity, within-word position, stress level of the previous and following vowels, phrasal position of the word containing the target consonant, its syllabic ...
Goubanova, Olga, King, Simon; id_orcid
core
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Moroccan Arabic Consonant Harmony:A Multiple Causation Hypothesis
Contemporary Moroccan Arabic has an innovative long-distance consonant harmony process. There are several possibilities of how this feature arose in Moroccan Arabic.
Zellou, Georgia
core
Investigating comparison of Chinese and Persian consonant sounds
In learning second language, the amount of similarity or difference between two language`s phonetic system, has an important effect on student`s learning.
نفیسه غضنفری
doaj

