Results 61 to 70 of about 198,472 (283)
Neural Dynamics of Phonetic Trading Relations for Variable-Rate CV Syllables [PDF]
The perception of CV syllables exhibits a trading relationship between voice onset time (VOT) of a consonant and duration of a vowel. Percepts of [ba] and [wa] can, for example, depend on the durations of the consonant and vowel segments, with an ...
Boardman, Ian+2 more
core +1 more source
Hermansky‐Pudlak syndrome type 1 (HPS‐1) is a rare, autosomal recessive disorder with poorly understood renal involvement. Urinary extracellular vesicle (uEV) proteomics and a novel Hps1 mouse model reveal mitochondrial abnormalities and lipid accumulation in HPS‐1 kidney proximal tubule cells. Serum ApoA1 correlates with kidney function in our patient
Dawn M. Maynard+7 more
wiley +1 more source
The human Na+/H+ antiporter NHA2 transports Na+ or Li+ in exchange for protons across cell membranes, and its dysfunction results in various pathologies, e.g., fertility disorders, hypertension, or diabetes. This work provides the molecular characterization of interactions of NHA2 with its specific inhibitor phloretin, which can be helpful for the ...
Olga Zimmermannova+3 more
wiley +1 more source
Consonant-Vowel-Consonants for Error-Free Code Entry
Codes and passwords are the bane of user experiences: even small mistakes can delay desired activities, causing undue frustration. Work on codes has focused on security instead of people’s ability to enter them error-free. Difficulties observed in a security demonstration motivated this investigation of code transcription difficulty. A pilot study with
Blanchard, Nikola, K+2 more
openaire +5 more sources
We describe a novel set of Epac‐based FRET‐FLIM biosensors with improved fully cytosolic distribution, achieved without compromising the state‐of‐the‐art performance of our original designs, for detecting cAMP dynamics in real time in live cells with high precision and reliability.
Giulia Zanetti+2 more
wiley +1 more source
Diphthamide synthesis is linked to the eEF2‐client chaperone machinery
The diphthamide modification of eukaryotic translation elongation factor 2 (eEF2) is important for accurate protein synthesis. We addressed the potential coordination of de novo eEF2 synthesis with simultaneous or subsequent diphthamide modification. Our work reveals that the co‐chaperones Hgh1 and Cpr7, which are known to support folding of nascent ...
Lars Kaduhr+4 more
wiley +1 more source
Concluding a series on meaningful word ladders, here\u27s another special type of ladder. Consonant cascades (CCs) are meaningful cases of consonant movements (CMs) in which all substitutions occur at the same position.
core +1 more source
Measuring consonant identification in nonsense syllables, words, and sentences.
Sensorineural hearing loss (SNHL) produces deficits in speech comprehension in noise that primarily are due to impairments in identifying consonants.
D. Woods, E. Yund, T. Herron
semanticscholar +1 more source
Proceedings of the Twenty-Ninth Annual Meeting of the Berkeley Linguistics Society: General Session and Parasession on Phonetic Sources of Phonological Patterns: Synchronic and Diachronic Explanations (2003)
William R. Leben+2 more
openaire +2 more sources
We explore 5HT2A receptor activation, a key target for psychedelic drugs, using molecular dynamics simulations. Without Gqα, the active receptor collapses to an inactive conformation, underscoring the G‐protein's role. Discovery of an intermediate “partially‐open” state and the higher affinity of ligands to the orthosteric binding site provides ...
Niklas Viohl+2 more
wiley +1 more source