Results 71 to 80 of about 186,668 (324)

Vacuolar transport and function of Saccharomyces cerevisiae sterol ester hydrolase Tgl1

open access: yesFEBS Letters, EarlyView.
Tgl1, one of yeast sterol ester hydrolases, had been found on the lipid droplets where sterol esters are mainly stored. This study revealed that Tgl1 is transported into the vacuole depending on the ESCRT‐I–III complex, and that it exhibits intra‐vacuolar sterol ester hydrolase activity.
Takumi Nakatsuji   +5 more
wiley   +1 more source

The role of fibroblast growth factors in cell and cancer metabolism

open access: yesFEBS Letters, EarlyView.
Fibroblast growth factor (FGF) signaling regulates crucial signaling cascades that promote cell proliferation, survival, and metabolism. Therefore, FGFs and their receptors are often dysregulated in human diseases, including cancer, to sustain proliferation and rewire metabolism.
Jessica Price, Chiara Francavilla
wiley   +1 more source

Comparing voiced and voiceless geminates in Sienese Italian: what role does preaspiration play? [PDF]

open access: yes, 2004
This paper compares the acoustic phonetic appearance of voiced & voiceless geminate stops in Sienese Italian. In our spontaneous speech data voiceless geminate stops are frequently preaspirated, which is an extremely rare phenomenon cross-linguistically.
Hajek, John, Stevens, Mary
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

open access: yesFEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

Gendang Melayu Sarawak (GMS) – Sarawak Malay Drum, the Dying and Forgotten Tradition

open access: yesBioResources
This work was conducted using the Picoscope signal extraction procedure, which revealed significant insights regarding the belian wood and its application in Gendang Melayu Sarawak (GMS) production.
Aaliyawani Ezzerin Sinin   +4 more
doaj   +2 more sources

Changes in the McGurk Effect Across Phonetic Contexts [PDF]

open access: yes, 2002
To investigate the process underlying audiovisual speech perception, the McGurk illusion was examined across a range of phonetic contexts. Two major changes were found.
Hampson, Michelle   +3 more
core  

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

open access: yesFEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino   +7 more
wiley   +1 more source

Comparing Speech Intelligibility in 3 to 5 Years Old Children with Cochlear Implants and Normal Children

open access: yesFunction and Disability Journal, 2018
Background and Objective: One of the positive outcomes of cochlear implantation is achieving intelligible speech. Therefore, the measurement of speech intelligibility is a standard criterion for assessing the effectiveness of cochlear implants (CIs). The
Mitra Sohrabi   +4 more
doaj  

Aided and unaided speech perception by older hearing impaired listeners.

open access: yesPLoS ONE, 2015
The most common complaint of older hearing impaired (OHI) listeners is difficulty understanding speech in the presence of noise. However, tests of consonant-identification and sentence reception threshold (SeRT) provide different perspectives on the ...
David L Woods   +5 more
doaj   +1 more source

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