Results 71 to 80 of about 215,037 (402)

FoxO1 signaling in B cell malignancies and its therapeutic targeting

open access: yesFEBS Letters, EarlyView.
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac   +3 more
wiley   +1 more source

Consonant lenition and phonological recategorization

open access: yes, 2011
We examine the weakening of intervocalic voiceless stops in Spanish in order to gain insight on historical processes of intervocalic lenition. In our corpus, about a third of all tokens of intervocalic /ptk/ are fully or partially voiced in spontaneous ...
J. Hualde   +2 more
semanticscholar   +1 more source

The immunological interface: dendritic cells as key regulators in metabolic dysfunction‐associated steatotic liver disease

open access: yesFEBS Letters, EarlyView.
Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi   +3 more
wiley   +1 more source

Analysis of the Word-Initial Segment with Reference to Lemmatising Zulu Nasal Nouns

open access: yesLexikos, 2012
<p>The process of lemmatising nasal nouns in the Zulu lexicon is problematic. The traditional method is to lemmatise a Zulu lexical noun by etymological noun-stem. This practice creates difficulties in harmonising lexical nouns with their syntactic
M.H. Mpungose
doaj   +1 more source

A cross-linguistic database of phonetic transcription systems [PDF]

open access: yes, 2018
Contrary to what non-practitioners might expect, the systems of phonetic notation used by linguists are highly idiosyncratic. Not only do various linguistic subfields disagree on the specific symbols they use to denote the speech sounds of languages, but
Anderson, C.   +6 more
core   +1 more source

Nasal consonant harmony at a distance the case of Yaka

open access: yesStudies in African Linguistics, 2010
In a number of Bantu languages the [d-l] reflex of Proto-Bantu *-Vd- suffixes alternates with [n] when the consonant of the preceding syllable is nasal, e.g., /dim-id-/ 'cultivate for' ~ [dim-in-].
Larry M. Hyman
semanticscholar   +1 more source

Insights into the renal pathophysiology in Hermansky‐Pudlak syndrome‐1 from urinary extracellular vesicle proteomics and a new mouse model

open access: yesFEBS Letters, EarlyView.
Hermansky‐Pudlak syndrome type 1 (HPS‐1) is a rare, autosomal recessive disorder with poorly understood renal involvement. Urinary extracellular vesicle (uEV) proteomics and a novel Hps1 mouse model reveal mitochondrial abnormalities and lipid accumulation in HPS‐1 kidney proximal tubule cells. Serum ApoA1 correlates with kidney function in our patient
Dawn M. Maynard   +7 more
wiley   +1 more source

Syntonets: Toward A Harmony-Inspired General Model of Complex Networks [PDF]

open access: yes, 2019
We report an approach to obtaining complex networks with diverse topology, here called syntonets, taking into account the consonances and dissonances between notes as defined by scale temperaments. Though the fundamental frequency is usually considered, in real-world sounds several additional frequencies (partials) accompany the respective fundamental,
arxiv   +1 more source

Subphonemic and suballophonic consonant variation : the role of the phoneme inventory [PDF]

open access: yes, 2013
Consonants exhibit more variation in their phonetic realization than is typically acknowledged, but that variation is linguistically constrained. Acoustic analysis of both read and spontaneous speech reveals that consonants are not necessarily realized ...
Lavoie, Lisa M.
core  

Cytosolic‐enhanced dark Epac‐based FRET sensors allow for intracellular cAMP detection in live cells via FLIM

open access: yesFEBS Letters, EarlyView.
We describe a novel set of Epac‐based FRET‐FLIM biosensors with improved fully cytosolic distribution, achieved without compromising the state‐of‐the‐art performance of our original designs, for detecting cAMP dynamics in real time in live cells with high precision and reliability.
Giulia Zanetti   +2 more
wiley   +1 more source

Home - About - Disclaimer - Privacy