Results 101 to 110 of about 36,911 (299)
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Pidginized English pronunciation in Thailand [PDF]
, 2007 Thailand Pidginized English Pronunciation (TPEP) is the pronunciation of English produced with a Thai accent. Its characteristics are systematic, stable and widely used and accepted within the country. This paper describes TPEP through an analysis of 12
Anont, Sukritta +3 more
core
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
LanguagesArabic phonotactics significantly differ from English phonotactics in that they usually follow a framework that forbids the presence of consonant clusters in syllabic onsets.
Abdel Rahman Mitib Altakhaineh +2 more
doaj +1 more source
Phono-semantically Motivated Lexical Patterns: Evidence from English and Modern Greek. [PDF]
, 2007 Generally, linguistic theory assumes that the association between sound and meaning is essentially arbitrary: a meaning can theoretically be represented by almost any set of sounds in a language.
Mela-Athanasopoulou, Elizabeth
core
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Was Proto-Kikongo a 5 or 7-vowel language? Bantu spirantization and vowel merger in the Kikongo language cluster [PDF]
, 2019 This article addresses whether Proto-Kikongo (PK), the most recent common ancestor of the Kikongo Language Cluster (KLC), should be reconstructed with an inventory of 5 or 7 vowel phonemes.
Bostoen, Koen, Goes, Heidi
core
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source