Results 111 to 120 of about 36,911 (299)

The Representation of the Phoneme /r/ in Ajabshir Turkish Dialect within Optimality Theory [PDF]

open access: yesمطالعات زبان‌‌ها و گویش‌های غرب ایران, 2018
This research is aimed to describe and analyze the representation of phoneme /r/ in different phonological environments in Ajabshir Turkish dialect within Optimality theoretical framework.
Seyed Mohammad Razinejad   +1 more
doaj  

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Revealing the effects of task complexity through digital storytelling on learning consonant clusters and language mindsets in EFL learners: A mixed-methods analysis

open access: yesActa Psychologica
While digital storytelling (DST) has gained recognition as an engaging pedagogical tool, there is a scarcity of research investigating how manipulating task complexity within DST activities impacts specific pronunciation skills and language mindsets ...
Ehsan Namaziandost, Ferdi Çelik
doaj   +1 more source

Early dialectal diversity in South Slavic I [PDF]

open access: yes, 2010
The large majority of the isoglosses which can be established in the South Slavic dialectal area date from the time of the disintegration of Common Slavic and from more recent periods (e.g., Ivi´c 1958: 25ff).
Kortlandt, Frederik H. H.
core  

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Is ʔ an Element? Towards a Non-segmental Phonology [PDF]

open access: yes, 1994
This paper argues that the element calculus of Government Phonology is overburdened. In particular it shows that the simple act of supposing extra elements to explain consonantal phenomena leads to far reaching and undesirable empirical consequences.
Jensen, Sean
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

A Polysystemic Approach, in Proto-Tibetan Reconstruction, to Tone and Syllable-Initial Consonant Clusters [PDF]

open access: yes, 1972
Allen   +38 more
core   +1 more source

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