Results 81 to 90 of about 53,993 (275)

Effects of tonal alignment on lexical identification in Italian

open access: yes, 2007
The aim of this paper is to examine the role of tonal alignment in Italian variety spoken in Naples. We focused on the effects of intonation in the perception of minimal pairs contrasting in consonant duration.
d'Imperio, Mariapaola   +2 more
core   +2 more sources

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

Degemination in Hungarian: phonology or phonetics? [PDF]

open access: yes, 2014
It is traditionally held with respect to Hungarian degemination that geminates do not occur in this language word initially or flanked by another consonant on either side.
Gráczi, Tekla Etelka, Siptár, Péter
core   +1 more source

A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy

open access: yesMolecular Oncology, EarlyView.
Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti   +3 more
wiley   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Timing the difference: A study of gemination in Dogri consonants

open access: yesActa Universitatis Carolinae: Philologica
This study examines the phonetic and phonological properties of singleton–geminate contrasts in Dogri within the context where the preceding vowel is short, i.e. in CVCV: word structures.
Pranav Badyal
doaj   +1 more source

The Timing Of Geminate Consonants In Tarifit Berber

open access: yesAL-Lisaniyyat, 2016
The main thrust of this investigation is to examine timing of gemination in Tarifit Berber (spoken in Northern Morocco) in order to find out if spatiotemporal phonetic characteristics underlying the production of Tarifit geminates may be captured from a phonological standpoint by a structural representation of these segments as two consecutive timing ...
Fayssal Bouarourou   +2 more
openaire   +2 more sources

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

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