Results 121 to 130 of about 25,115 (305)
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
The Phonetics and Phonology of Geminate Consonants
, 2017 Geminate consonants, also known as long consonants, appear in many languages in the world, and how they contrast with their short counterparts, or singletons (e.g. /tt/ vs.
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FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
, 1969 The twenty-two words needed to complete this puzzle are composed mostly of consonants. Indeed, only eight of the words contain any vowels.
Porter, Temple G.
core
FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
North Norwegian consonants from the inside
, 2014 This study contains MRI recordings of consonants produced by a native of Tromsø. Each consonant is produced between two low vowels: a__a. The files are labelled with intuitive orthographic renderings of the consonants.
Krämer, Martin, Albertsen, Egil
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Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Articulation of whispered alveolar consonants
, 2011 This thesis explores the articulation of whispered and normally-spoken alveolar consonants through the use of electropalatography (EPG). While whisper is a well-researched topic, most prior studies have been limited to glottal and acoustic examinations ...
Osfar, Megan J.
core
DAL002-005 - Dalabon consonants
Illustrations of Dalabon consonants in initial, medial and final position, going through the table in Phonology chapter. Original filenames: Da20150526eI.wav, Da20150526eM.wav, Da2015ConsonantIllustrations.eaf..
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