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Results 271 to 280 of about 188,688 (357)

Covalent Reprogramming of Kinase Binders to Modulate Protein Abundance

Advanced Science, EarlyView.
Electrophilic remodeling of a broad‐spectrum kinase binder reveals how subtle chemical changes reprogram protein fate. An acrylamide analog of a multi‐kinase binder selectively stabilizes Aurora kinase A (AURKA) by suppressing its ubiquitination, while a short‐linker variant converts this stabilizer into a degrader.
Chen Mozes +4 more
wiley +1 more source

Multi-omics provides functional insights and underscores practical challenges in assessing the composition and performance of a nitrifying microbial consortium. [PDF]

Appl Environ Microbiol
Smith DDN, Subasinghe RM, Kehoe C, Grégoire DS. +3 more
europepmc +1 more source

Toward Predictive Theory in Single‐Atom Catalysis

Advanced Science, EarlyView.
A lifecycle‐oriented framework reframes modeling in single‐atom catalysis. By combining ensemble‐based descriptions with explicit validation against experimental observables, the approach defines the scope of theory across catalyst synthesis, activity, stability, and safety, clarifying where quantitative insight is possible and where interpretation ...
Andrea Ruiz‐Ferrando +3 more
wiley +1 more source

Adopting omics-based approaches to facilitate the establishment of microbial consortia to generate reproducible fermented foods with desirable properties. [PDF]

NPJ Sci Food
Zhang E, Claesson MJ, Cotter PD.
europepmc +1 more source

Integration and innovation: medical and health consortia improving continuing medical education in China. [PDF]