Results 51 to 60 of about 1,617,594 (350)

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

Unity is strength: creation and future actions for a consortium for HIV cure research in Latin America and the Caribbean ‘Lac-Cura’

HIV Research & Clinical Practice
The development of effective HIV cure strategies is crucial. However, most research in this area has been concentrated in high-income countries, underscoring the need to expand efforts to regions like Latin America and the Caribbean (LAC), which face ...
Gabriela Turk, Gastón Devisich, Fernando Valiente-Echeverria, María Inés Figueroa, Isabel Cassetti, Pedro Cahn, Claudia P. Cortes, Brenda Crabtree-Ramírez, Omar Sued, Natalia Laufer   +9 more
doaj   +1 more source

Case Summary: Dada Dhaka and Max Embo (Bangladesh) [PDF]

, 2008
WRC report on assessment of labor rights violations found in the Dada Dhaka and Max Embo factories in Bangladesh.
Worker Rights Consortium
core   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Produção de diferentes variedades de mandioca em sistema agroecológico Growth and production of different cassava varieties in an agroeological system

Revista Brasileira de Engenharia Agrícola e Ambiental, 2009
Neste trabalho, conduzido na comunidade de Morro Alto, município de Acauã, PI, localizada na Serra da Parreira, situada a 620 m de altitude, objetivou-se avaliar o crescimento e a produção da mandioca em cultivo consorciado com guandu, sorgo, caupi ...
Alineaurea F. Silva, Luiz M. de Santana, Carla R. R. S. França, Clésio A. de S. Magalhães, Cândido R. de Araújo, Sérgio G. de Azevedo   +5 more
doaj   +1 more source

Implementation of Blockchain Consortium to Prioritize Diabetes Patients’ Healthcare in Pandemic Situations

IEEE Access, 2021
Diabetes is a metabolic disorder caused by high blood sugar levels, which can harm the kidneys, the heart, the eyes, and blood vessels. During the Covid-19 pandemic, diabetes patients were most affected. In the existing healthcare system, medical data is
Ganesan Subramanian, Anand Sreekantan Thampy   +1 more
doaj   +1 more source

Model Code of Conduct [PDF]

, 2005
Code of conduct to be adopted by WRC member schools and colleges as the standard they will require of licensees.
Workers’ Rights Consortium
core   +1 more source

The ProteomeXchange consortium in 2020: enabling ‘big data’ approaches in proteomics

Nucleic Acids Res., 2019
The ProteomeXchange (PX) consortium of proteomics resources (http://www.proteomexchange.org) has standardized data submission and dissemination of mass spectrometry proteomics data worldwide since 2012.
E. Deutsch, N. Bandeira, Vagisha Sharma, Yasset Pérez-Riverol, Jeremy J. Carver, D. J. Kundu, D. García-Seisdedos, Andrew F. Jarnuczak, Suresh Hewapathirana, B. Pullman, J. Wertz, Zhi Sun, S. Kawano, Shujiro Okuda, Yu Watanabe, H. Hermjakob, B. MacLean, M. MacCoss, Yun-ping Zhu, Y. Ishihama, J. Vizcaíno   +20 more
semanticscholar   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Assessment of productive parameters in broilers and supplemented by probiotic microorganisms

Temas Agrarios, 2015
Poultry systems intended for the production of broilers usually handle high poultry densities to obtain a higher production rate of meat by confinement area, situation that results in animal stress and thus zootechnical low yields.
Luz A. Gutiérrez, Oswaldo Bedoya, Juan E. Arenas   +2 more
doaj   +1 more source