Results 61 to 70 of about 1,617,594 (350)

WRC Letter to the FLA (re: opposition to Designated Suppliers Program) [PDF]

, 2006
This letter is written in response to the FLA’s opposition to the WRC’s Designated Suppliers Program guidelines regarding the program’s impact on countries which bar independent unions, associational rights, living wage, antitrust issues, the selection ...
Worker Rights Consortium
core   +1 more source

Management of patients with increased risk for familial pancreatic cancer: updated recommendations from the International Cancer of the Pancreas Screening (CAPS) Consortium

Gut, 2019
Background and aim The International Cancer of the Pancreas Screening Consortium met in 2018 to update its consensus recommendations for the management of individuals with increased risk of pancreatic cancer based on family history or germline mutation ...
M. Goggins, K. Overbeek, R. Brand, S. Syngal, M. Chiaro, D. Bartsch, C. Bassi, A. Carrato, J. Farrell, E. Fishman, P. Fockens, T. Gress, J. Hooft, R. Hruban, F. Kastrinos, F. Kastrinos, A. Klein, A. Lennon, A. Lucas, Walter G. Park, A. Rustgi, D. Simeone, E. Stoffel, H. Vasen, D. Cahen, M. Canto, M. Bruno   +26 more
semanticscholar   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Worker Rights Consortium Assessment Jerzees de Honduras (Russell Corporation): Findings and Recommendations [PDF]

, 2008
WRC report on its assessment of workers’ rights at the Jerzees factory in Honduras as the plant announced its closure.
Worker Rights Consortium
core   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

State and Local Government Sweatfree Consortium: Why the Consortium is Good for Business [PDF]

, 2007
This document is part of a digital collection provided by the Martin P. Catherwood Library, ILR School, Cornell University, pertaining to the effects of globalization on the workplace worldwide.
International Labor Rights Forum, Sweatfree Communities   +1 more
core   +1 more source

Defining high bleeding risk in patients undergoing percutaneous coronary intervention: a consensus document from the Academic Research Consortium for High Bleeding Risk

European Heart Journal, 2019
Identification and management of patients at high bleeding risk undergoing percutaneous coronary intervention are of major importance, but a lack of standardization in defining this population limits trial design, data interpretation, and clinical ...
P. Urban, R. Mehran, R. Colleran, D. Angiolillo, R. Byrne, D. Capodanno, T. Cuisset, D. Cutlip, P. Eerdmans, J. Eikelboom, A. Farb, C. Gibson, J. Gregson, M. Haude, S. James, Hyo‐Soo Kim, Takeshi Kimura, A. Konishi, J. Laschinger, M. Leon, P. A. Magee, Yoshiaki Mitsutake, D. Mylotte, S. Pocock, M. Price, S. Rao, Ernest Spitzer, Ernest Spitzer, N. Stockbridge, M. Valgimigli, O. Varenne, Ute Windhoevel, R. Yeh, Mitchell W. Krucoff, Mitchell W. Krucoff, M. Morice   +35 more
semanticscholar   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Empowering professional learning communities of secondary science teachers to uncover and address their students’ misconceptions via research-oriented practices

Frontiers in Education
The Partnership for the Development and Success of Science Education in Secondary Schools project seeks to improve science education by fostering a dynamic environment for professional development and teacher-led inquiry within professional learning ...
Patrice Potvin, Bénédicte Boissard, Éric Durocher, Abdelkrim Hasni, Martin Riopel   +4 more
doaj   +1 more source

Study of the dynamics of the development of lactic acid microorganisms in the two-stage process of fermenting cabbage varieties "Parus"

Овощи России, 2019
Relevance. Leuconostoc mesenteroides, Lactobacillus plantarum and Leuconostoc fallaxare the three main lactic acid bacteria developing in the production of sauerkraut.
Vladimir V. Kondratenko, Nataliya E. Posokina, Jeanne A. Semenova, Vladimir I. Tereshonok   +3 more
doaj   +1 more source