Results 41 to 50 of about 2,711,142 (273)

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

FEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey, Miriam Livier Llamas‐García, Gabriela M. Montero‐Morán, Leticia Santos, Samuel Lara‐González   +4 more
wiley   +1 more source

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

FEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen, Duc Trung Nguyen, Minyoung Cho, Jihun Kim, Soyeon In, Thai Uy Nguyen, Sunghoon Hurh, Beom Jin Park, Jong‐Ik Hwang   +8 more
wiley   +1 more source

Effect of high temperature cyclic loading on γ′ phase evolution behavior of DZ411 alloy

Journal of Aeronautical Materials
Optical microscopy（OM） and scanning electron microscopy （SEM） methods are employed to investigate the effect of various load conditions—including a constant load of 200 MPa，an average stress of 200 MPa with a stress amplitude of 130 MPa，and an average ...
ZHENG Wuyue, ZHI Yiheng, ZHOU Tongtong, CAO Tieshan, CHENG Congqian, ZHAO Jie   +5 more
doaj   +1 more source

Observer‐Based Adaptive Event‐Triggered Tracking Control for Fuzzy TS Systems With Premise Mismatch

International Journal of Adaptive Control and Signal Processing, EarlyView.
This paper presents an adaptive logistic event‐triggered observer‐based tracking controller for Takagi‐Sugeno fuzzy systems under constrained inputs and network delays. Leveraging a hybrid LMI and Secretary Bird Optimization approach, this strategy significantly minimizes communication overhead and computational burden while ensuring optimal reference ...
Oussama Djadane, Salama Makni, Mourad Kchaou, Ahmed El Hajjaji   +3 more
wiley   +1 more source

The effect of weld residual stresses and their re-distribution with crack growth during fatigue under constant amplitude loading [PDF]

, 2010
In this work the evolution of the residual stresses in a MIG-welded 2024-T3 aluminium alloy M(T) specimen during in situ fatigue crack growth at constant load amplitude has been measured with neutron diffraction.
Lin, J., Liljedahl, C. D. M., Fitzpatrick M, Edwards, L., Edwards, Lyndon, Fitzpatrick, Michael E., Zanellato, O., Fitzpatrick, M. E., Edwards L, Zanellato, Oliver, Liljedahl C, Liljedahl, C. David M., Lin J, Zanellato O, Liljedahl, CDM, Edwards, L, Lin, J, Fitzpatrick, ME, Zanellato, O   +18 more
core   +1 more source

Characterization of Defect Distribution in an Additively Manufactured AlSi10Mg as a Function of Processing Parameters and Correlations with Extreme Value Statistics

Advanced Engineering Materials, EarlyView.
Predicting extreme defects in additive manufacturing remains a key challenge limiting its structural reliability. This study proposes a statistical framework that integrates Extreme Value Theory with advanced process indicators to explore defect–process relationships and improve the estimation of critical defect sizes. The approach provides a basis for
Muhammad Muteeb Butt, Varma Kvvssn, Hossein Laieghi, Zia Uddin, Peyman Ansari, E. Kıvanç Sadak, Can Barış Toprak, Hüseyin Kızıl, Enrico Salvati   +8 more
wiley   +1 more source

Fatigue and Crack Growth under Constant- and Variable-Amplitude Loading in 9310 Steel Using “Rainflow-on-the-Fly” Methodology

Metals, 2021
Fatigue of materials, like alloys, is basically fatigue-crack growth in small cracks nucleating and growing from micro-structural features, such as inclusions and voids, or at micro-machining marks, and large cracks growing to failure.
James C. Newman
doaj   +1 more source

Microstructural Evolution and Vacancy Defect Formation in Mn–Mo–Ni RPV Steel Under Low Cycle Fatigue: Insights From EBSD and PALS

Advanced Engineering Materials, EarlyView.
Low‐cycle fatigue damage in Mn–Mo–Ni reactor pressure vessel steel is examined using a combined electron backscatter diffraction and positron annihilation lifetime spectroscopy approach. The study correlates texture evolution, dislocation substructure development, and vacancy‐type defect formation across uniform, necked, and fracture regions, providing
Apu Sarkar, Dhanadeep Dutta, G. Bharat Reddy   +2 more
wiley   +1 more source

Cyclic deformation and fatigue data for Ti–6Al–4V ELI under variable amplitude loading

Data in Brief, 2017
This article presents the strain-based experimental data for Ti–6Al–4V ELI under non-constant amplitude cyclic loading. Uniaxial strain-controlled fatigue experiments were conducted under three different loading conditions, including two-level block ...
Patricio E. Carrion, Nima Shamsaei, Robert D. Moser   +2 more
doaj   +1 more source

Fatigue behavior of the transverse stiffener subjected to constant amplitude loading

KSCE Journal of Civil Engineering, 2002
Objectives of this study are to examine the fatigue behavior of the transverse stiffener in comparison with other previous studies. The shape of fatigue cracks depended upon the number of crack initiation sites along the weld toe. Fatigue cracks initiated at a corner had quarter-elliptical fronts.
openaire   +1 more source