Results 91 to 100 of about 5,299,339 (300)

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Why human connection is the true metric of research success

open access: yesFEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan   +3 more
wiley   +1 more source

Design of a constant current driving circuit of eddy current sensor

open access: yesGong-kuang zidonghua, 2014
In view of problems that using open-loop constant voltage to drive eddy current sensor may suffer from drive current variation with temperature drift and load change, a constant current driving circuit of eddy current sensor using linear control theory ...
JIANG Guodong, DING Qiang
doaj   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

open access: yesFEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin   +12 more
wiley   +1 more source

Universal Design Method of Load‐Independent Constant Voltage and Constant Current Outputs for Capacitive Power Transfer System

open access: yesIET Power Electronics
In the field of wireless power transfer technology, capacitive power transfer (CPT) technology has received more and more attention due to its numerous advantages.
Gang Yang   +5 more
doaj   +1 more source

Experimental Results and Analysis of Wireless Charging Technology for Equipment Under Seawater

open access: yesWorld Electric Vehicle Journal
A constant current constant voltage charging scheme based on a single-ended primary inductive converter is proposed to address the key issues of wireless power transfer (WPT) technology for charging devices in seawater environments.
Saisai Hu, Wangqiang Niu
doaj   +1 more source

The constant current loop: A new paradigm for resistance signal conditioning [PDF]

open access: yes
A practical, single, constant-current loop circuit for the signal conditioning of variable-resistance transducers was synthesized, analyzed, and demonstrated.
Anderson, Karl F.
core   +1 more source

Constant Current vs Constant Voltage ECT Devices [PDF]

open access: yesBritish Journal of Psychiatry, 1988
R D, Weiner, C E, Coffey
openaire   +2 more sources

Prognostic Impact of European LeukemiaNet Genetic Risk Stratification System in Adult Patients With Acute Myeloid Leukemia

open access: yesAging and Cancer, EarlyView.
This study aimed to evaluate the prognostic value of ELN2017 in predicting survival outcomes and to assess the impact of clinical and molecular factors such as age, FLT3 and NPM1 mutations, and allogeneic hematopoietic stem cell transplantation (allo‐HSCT).
Mobina Shrestha   +4 more
wiley   +1 more source

Lessons Learned From a Delayed‐Start Trial of Modafinil for Freezing of Gait in Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Freezing of gait (FOG) in people with Parkinson's disease (PwPD) is debilitating and has limited treatments. Modafinil modulates beta/gamma band activity in the pedunculopontine nucleus (PPN), like PPN deep brain stimulation. We therefore tested the hypothesis that Modafinil would improve FOG in PwPD.
Tuhin Virmani   +8 more
wiley   +1 more source

Home - About - Disclaimer - Privacy