Results 41 to 50 of about 258,433 (264)

A New Topological Method for Output Voltage Clamping of Immittance-based Constant Current Load Resonant Converters [PDF]

Journal of Applied Research in Electrical Engineering
In this paper a new improved diode-based circuit is introduced for output voltage limiting of immittance-based constant current Load Resonant Converters (LRCs).
Alireza Khoshsaadat, Mohammad Abedini
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

AscF in the mycobacterial CIII–CIV supercomplex lacks metal and nucleotide binding but links malate oxidation to respiration

FEBS Letters, EarlyView.
The mycobacterial CIII‐CIV respiratory supercomplex is an obligate assembly, encompassing several subunits of unknown functions. We have characterized the intracellular subunit AscF, and show that it is unlikely to be a sensor for metals or nucleotides, but is required for growth on nonfermentable energy sources, and likely works as an adapter for ...
Eni Rile, Riccardo Diamanti, Daniel Lundin, Soni Sharma, Robin Lissner, Coenraad P. Kuil, Martin Högbom, Dirk Bald, Dan Sjöstrand   +8 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

High‐efficiency multi‐string LED driver based on constant current bus with time‐multiplexing control

Electronics Letters, 2016
A high‐efficiency multi‐string LED driver based on constant current bus with time‐multiplexing control scheme is proposed and analysed. Each LED string is connected to the constant current bus, which is provided by the output of a front‐end high ...
Xueshan Liu, Jianping Xu, Qi Yang, Duo Xu   +3 more
doaj   +1 more source

An LCC-P Compensated Wireless Power Transfer System with a Constant Current Output and Reduced Receiver Size

Energies, 2019
Wireless Power Transfer (WPT) for autonomous underwater vehicles (AUVs) has been a research focus in recent years. This paper studies the inductor-capacitor-capacitor and parallel (LCC-P) compensation topology to achieve a compact receiver for AUVs ...
Zhengchao Yan, Yiming Zhang, Baowei Song, Kehan Zhang, Tianze Kan, Chris Mi   +5 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

An optically coupled power stimulus isolation unit with high voltage and fast rise time output

Brazilian Journal of Medical and Biological Research, 1999
Recent technological developments have created new devices that could improve and simplify the construction of stimulus isolators. HEXFET transistors can switch large currents and hundreds of volts in nanoseconds.
R.O. Brasil, J.H. Leal-Cardoso
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Input-parallel–output-series control strategy for three-level medium-voltage DC grid-type converter

The Journal of Engineering, 2019
A control topology input-parallel–output-series converter system is investigated, which is suitable for high-voltage and high-output power applications.
Faisal Mehmood Shah, Wenqiang Xie, Wenqiang Xie, Wen Li Yan, Rui Li, Han Minxiao, Girmaw Teshager Bitew   +6 more
doaj   +1 more source