Results 61 to 70 of about 10,828,712 (247)

An LED Drive Circuit with Constant-Output-Current Control and Constant-Luminance Control [PDF]

open access: yes
A Single LED is very small, and their luminance is related to the amount of driving current. Sufficient luminance for an illuminator requires many LEDs to be connected together and a constant current supplied to each LED. Therefore, the LED drive circuit
Nishikawa, Masahiro   +3 more
core  

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

open access: yesMolecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim   +11 more
wiley   +1 more source

DC-DC Boost Converter with Constant Output Voltage for Grid Connected Photovoltaic Application System [PDF]

open access: yes, 2010
The main purpose of this paper is to introduce an approach to design a DC-DC boost converter with constant output voltage for grid connected photovoltaic application system.
Chan, Pui Weng
core  

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Estimating the Inflation-Output Variability Frontier with Inflation Targeting: A VAR Approach [PDF]

open access: yes
This paper (i) illustrates how a VAR model can be used to evaluate inflation targeting, (ii) derives the policy frontier available to the central bank using counterfactual experiments with real time data, and (iii) estimates how this frontier has changed
W. Douglas McMillin, James S. Fackler
core   +2 more sources

A Constant Voltage/Current CPT System With Lightweight Characteristics for the Unmanned Aerial Vehicle

open access: yesIEEE Access
The large weight of the unmanned aerial vehicle (UAV) could cause a decrease in endurance mileage, while poor anti-offset performance could extend charging time and may even damage onboard equipment.
Yufang Chang   +4 more
doaj   +1 more source

The effects on arterial haemoglobin oxygen saturation and on shunt of increasing cardiac output with dopamine or dobutamine during one-lung ventilation [PDF]

open access: yes, 2004
Publisher's copy made available with the permission of the publisher © Australian Society of AnaesthetistsTheoretically, if the cardiac output were increased in the presence of a given intrapulmonary shunt, the arterial saturation should improve as the ...
Russell, W., James, M.
core   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

open access: yesFEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo   +6 more
wiley   +1 more source

A High Efficiency Charging Strategy for a Supercapacitor Using a Wireless Power Transfer System Based on Inductor/Capacitor/Capacitor (LCC) Compensation Topology

open access: yesEnergies, 2017
In the application of rail transit vehicles, when using typical wireless power transfer (WPT) systems with series–series (SS) compensation supply power for supercapacitors, the output current is in an approximately inverse relationship with the duty ...
Yuyu Geng   +4 more
doaj   +1 more source

Identifying and characterising a plant GH1 β‐glucosidase that exhibits hydrolytic activity on N‐linked glucopyranoside

open access: yesFEBS Open Bio, EarlyView.
We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli   +3 more
wiley   +1 more source

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