Results 81 to 90 of about 48,603 (267)

Prediction of Myasthenia Gravis Worsening: A Machine Learning Algorithm Using Wearables and Patient‐Reported Measures

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is a rare disorder characterized by fluctuating muscle weakness with potential life‐threatening crises. Timely interventions may be delayed by limited access to care and fragmented documentation. Our objective was to develop predictive algorithms for MG deterioration using multimodal telemedicine data ...
Maike Stein, Haoqi Sun, Sophie Lehnerer, Lea Gerischer, Maximilian Mönch, Christian Meisel, Andreas Meisel, Pushpa Narayanaswami   +7 more
wiley   +1 more source

The torsion, the local conical constants and their application in corneal topography [PDF]

EPJ Web of Conferences
Elevation topography equipment measures freeform surfaces by representing the surface with elevation maps, maximum curvature, minimum curvature, mean curvature, and Gaussian curvature.
Valencia-Estrada Juan, Valencia-Estrada Alejandro, Vázquez-Dorrío Benito, García-Márquez Jorge   +3 more
doaj   +1 more source

Stability of surfaces with constant mean curvature [PDF]

Proceedings of the American Mathematical Society, 1989
The notion of stability for surfaces with constant mean curvature H used in this paper is not the appropriate one. It requires the second variation of area to be positive for all compactly supported variations, and not only for those that preserve volume. This is such a strong definition that with it round spheres are not stable [cf. \textit{J.
openaire   +2 more sources

Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz, Christopher H. Thompson, Linda C. Laux, Alfred L. George Jr.   +3 more
wiley   +1 more source

Hip Morphology–Based Osteoarthritis Risk Prediction Models: Development and External Validation Using Individual Participant Data From the World COACH Consortium

Arthritis Care &Research, EarlyView.
Objective This study aims to develop hip morphology‐based radiographic hip osteoarthritis (RHOA) risk prediction models and investigates the added predictive value of hip morphology measurements and the generalizability to different populations. Methods We combined data from nine prospective cohort studies participating in the Worldwide Collaboration ...
Myrthe A. van den Berg, Fleur Boel, Michiel M. A. van Buuren, Noortje S. Riedstra, Jinchi Tang, Harbeer Ahedi, Nigel K. Arden, Sita M. A. Bierma‐Zeinstra, Cindy G. Boer, Flavia M. Cicuttini, Timothy F. Cootes, David T. Felson, Willem Paul Gielis, Joshua Heerey, Graeme Jones, Stefan Kluzek, Nancy E. Lane, Claudia Lindner, Joyce B. J. van Meurs, Andrea Mosler, Amanda E. Nelson, Michael C. Nevitt, Edwin H. Oei, Jos Runhaar, Harrie Weinans, Jesse H. Krijthe, Rintje Agricola   +26 more
wiley   +1 more source

Sarilumab in Polyarticular‐Course Juvenile Idiopathic Arthritis: Dose‐Finding and One‐Year Analysis of a Phase 2b, Open‐Label, Multicenter Study

Arthritis Care &Research, Accepted Article.
Objective This study assessed sarilumab in treating patients with polyarticular‐course juvenile idiopathic arthritis (pcJIA). Methods This phase 2b, open‐label study (NCT02776735) consisted of three sequential parts (each with a core‐treatment and extension‐phase). During part 1, three doses were assessed in two weight groups (Group A/B: ≥30–60 kg/≥10–<
Fabrizio De Benedetti, Inmaculada C. Penadés, Irina Nikishina, Ivan Foeldvari, Alberto J. Spindler, Anna Kozlova, Nadina Rubio‐Pérez, Pierre Quartier, Zbigniew Żuber, Raul Barria, Daniel Clemente, Gabriel V. Cornejo, Katherine Marzan, Nancy Liu, Christine Xu, Stephen DiMartino, Angeliki Giannelou, Fei Cao‐Ghoul, Bolanle Akinlade, Lydie Baret‐Cormel   +19 more
wiley   +1 more source

Null scrolls with prescribed curvatures in Lorentz-Minkowski 3-space

Analele Stiintifice ale Universitatii Ovidius Constanta: Seria Matematica, 2020
In Lorentz-Minkowski 3-space, null scrolls are ruled surfaces with a null base curve and null rulings. Their mean, as well as their Gaussian curvature, depends only on a parameter of a base curve. In the present paper, we obtain the first-order nonlinear
Šipuš Željka Milin, Gajčić Ljiljana Primorac, Protrka Ivana   +2 more
doaj   +1 more source

Validation of a Genetic Risk Score Combined With Clinical Variables for Predicting Pulmonary Fibrosis in Early Rheumatoid Arthritis

Arthritis Care &Research, EarlyView.
Objective Pulmonary fibrosis (PF) is a severe extra‐articular manifestation of rheumatoid arthritis (RA). This study aimed to externally validate a genetic risk score (GRS) and a combined risk score (CRS) for predicting the risk of RA‐associated PF in an independent cohort of patients with early RA.
Mikael Brink, Austin Wheeler, Bryant R. England, Solbritt Rantapää‐Dahlqvist   +3 more
wiley   +1 more source

Timelike Bonnet surfaces with non-constant curvature

Sakarya Üniversitesi Fen Bilimleri Enstitüsü Dergisi, 2013
In this study, the criterion of a timelike surface being Bonnet surface in 3-dimensional Minkowski space given by [11] is taken into consideration and by a similar manner of the classification of surfaces in Euclidean space done by I. M.
Soley Ersoy, Kemal Eren
doaj   +1 more source

Stability of hypersurfaces with constant mean curvature

Mathematische Zeitschrift, 1984
Let \(x:{\text M}^{n}\rightarrow\,{\text R}^{n+1}\) be an immersion of an orientable, n-dimensional manifold \({\text M}^{n}\) into the euclidean space \({\text R}^{n+1}\). The condition that x has nonzero constant mean curvature H = H 0 is known to be equivalent to the fact that xis a critical point of a variational problem.
Barbosa, Joao, do, Carmo Manfredo
openaire   +2 more sources