Results 51 to 60 of about 165,452 (304)

Constant beamwidth generalised sidelobe canceller

open access: yes, 2005
In this paper, we proposed a constant beamwidth discrete Fourier transform (DFT) beamformer based on the generalised sidelobe canceller (GSC). Broadband signals are decomposed into frequency bins which are grouped into octaves and tapered individually ...
Weiss, Stephan   +5 more
core   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Law of Shear wave speed in Shear Wave Imaging

open access: yes工程科学与技术, 2011
: Radiation force from ultrasound has been used to excite monochromatic waves in tissues. The shear wave propagation speed is related to the shear elasticity and shear viscosity of the tissue.
Yin Yuan-Yuan   +4 more
doaj  

Development of ΔK-decreasing test method of the metal film by displacement constraint along the elliptical through hole-edge

open access: yesMechanical Engineering Journal, 2016
A new ΔK-decreasing test method of the metal film was developed. The film was adhered to a through elliptical hole in a base plate and was fatigued in accordance with the displacement constraint along the hole-circumference in the base plate subjected to
Kenichi SHIMIZU, Yu KATO, Fumiya SAKATA
doaj   +1 more source

Propagation of a Modified Complex Lorentz–Gaussian-Correlated Beam in a Marine Atmosphere

open access: yesPhotonics, 2021
In this paper, we study the second-order statistics of a modified complex Lorentz–Gaussian-correlated (MCLGC) beam, which is a new type of partially coherent beam capable of producing an Airy-like intensity pattern in the far field, propagation through ...
Baoyin Sun   +4 more
doaj   +1 more source

Effects of Assuming Constant Optical Scattering on Haemoglobin Concentration Measurements Using NIRS during a Valsalva Manoeuvre

open access: yes, 2011
Resolving for changes in concentration of tissue chromophores in the human adult brain with near-infrared spectroscopy has generally been based on the assumption that optical scattering and pathlength remain constant.
Cooper, CE   +20 more
core   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Fatigue Crack Propagation Path and Life Prediction Based on XFEM

open access: yesXibei Gongye Daxue Xuebao, 2019
Based on the theory of linear elastic fracture mechanics, the relationships between material constants c3, c4 required in Abaqus and constants C, m in Paris formula are derived.

doaj   +1 more source

The fermion propagator in cosmological spaces with constant deceleration [PDF]

open access: yesClassical and Quantum Gravity, 2009
18 pages, 1 figure, published ...
Koksma, J.F., Prokopec, T.
openaire   +4 more sources

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

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