Results 111 to 120 of about 654,561 (303)
Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende +26 more
wiley +1 more source
Geomechanics and Geophysics for Geo-Energy and Geo-ResourcesThe feasibility of microwave heating-assisted rock breakage technology in geotechnical engineering has been widely explored. However, the limited knowledge of the impact of the contrast properties between different bedding planes and outer formation ...
Hongwen Yu +5 more
doaj +1 more source
Structural integrity assessment of superheater outlet penetration tubeplate
, 2009 In recent years, the Linear Matching Method (LMM) has been well developed for the integrity assessment of the component subjected to cyclic thermal and mechanical loads.
Haofeng Chen +3 more
core +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang +8 more
wiley +1 more source
Problematic Internet Use in Frontotemporal Dementia: A Case Series
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT The present study investigated problematic internet use (PIU) among 61 patients with frontotemporal dementia (FTD) compared to a cohort of 354 patients with mild cognitive impairment (MCI) and Alzheimer's dementia. PIU was identified in 22.9% of FTD patients compared to only 0.8% of AD patients (p < 0.001). Behaviors included compulsive social
Daniele Urso +9 more
wiley +1 more source
Living in constant crisis--when stress management becomes the problem. [PDF]
PLoS Biology, 2014 Roland G Roberts
doaj +1 more source
Arthritis Care &Research, EarlyView.Objective Although the definition of a gout flare is well established, the state of gout flare resolution has not yet been defined. This study aimed to explore patients’ experiences and perceptions of gout flare resolution. Methods Semistructured interviews were conducted with 24 people with gout, guided by open‐ended questions exploring their ...
Sarah Stewart +5 more
wiley +1 more source
TRANSACTIONS OF THE JAPAN SOCIETY OF MECHANICAL ENGINEERS Series A, 1989 In X-ray stress measurement, to obtain accurate results, it is necessary to determine experimentally the X-ray stress constant. However, values measured by X-ray diffraction have variability arising from inherent X-ray counting statistics. Therefore, it is important to investigate the reproducibility of the measured values by using the standard ...
openaire +2 more sources
, 2018 The stress-strain relationship of FRP confined concrete columns under eccentric loading is different from that under concentric loading. However, eccentric loading can have different load paths, e.g. constant axial force with increasing load eccentricity
Yufei Wu (19970451) +2 more
core
β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations
Advanced Biology, Volume 9, Issue 3, March 2025.Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio +11 more
wiley +1 more source