Results 91 to 100 of about 471,133 (346)
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
A novel soft switching crossing current resonant converter (XCRC) [PDF]
, 1994 Unlike other resonate or soft-switching converter, this novel topology employs only two switches and a very simply control method. The inherent constant power protection feature is another merit. No special resonate chip is needed to control the circuit.
Pong, MH, Poon, FNK
core +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Model $I$--$V$ curves and figures of merit of underdamped deterministic Josephson ratchets
, 2016 We propose simple models for the current-voltage characteristics of typical Josephson ratchets. We consider the case of a ratchet working against a constant applied counter force and derive analytical expressions for the key characteristics of such a ...
Goldobin, E. +3 more
core +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Active Battery Voltage Equalization Based on Chain-Loop Comparison Strategy
EnergiesThis paper describes active battery balancing based on a bidirectional buck converter, a flyback converter, and battery cells by using the proposed chain-loop comparison strategy.
Kuo-Ing Hwu +2 more
doaj +1 more source
Integrated quantized electronics: a semiconductor quantized voltage source
, 2011 The Josephson effect in superconductors links a quantized output voltage Vout = f \cdot(h/2e) to the natural constants of the electron's charge e, Planck's constant h, and to an excitation frequency f with important applications in electrical quantum ...
Fricke, Lukas +9 more
core +1 more source
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
High-Efficiency, Low-Power, Fully Integrated Neural Electrical Stimulation Circuit
Applied SciencesThis paper presents a highly efficient, low-power, fully integrated neural stimulation circuit implemented using solely low-voltage devices. The circuit primarily consists of a high-voltage-generation circuit, an output driver circuit, and a constant ...
Yujiao Wang, Jiahao Cheong, Cheng Liu
doaj +1 more source