Results 91 to 100 of about 471,152 (307)

Effects of Biological Sex and Age on Cerebrospinal Fluid Markers—A Retrospective Observational Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cerebrospinal fluid (CSF) analysis is a key diagnostic tool for neurological diseases. To date, only a few studies have investigated in larger cohorts the effect of age and biological sex on diagnostic markers extracted from CSF. Methods For this retrospective observational study, 4163 CSF findings (2012–2020) were evaluated.
Isabel‐Sophie Hafer   +3 more
wiley   +1 more source

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende   +26 more
wiley   +1 more source

Active Battery Voltage Equalization Based on Chain-Loop Comparison Strategy

open access: yesEnergies
This paper describes active battery balancing based on a bidirectional buck converter, a flyback converter, and battery cells by using the proposed chain-loop comparison strategy.
Kuo-Ing Hwu   +2 more
doaj   +1 more source

Transistorized converter provides nondissipative regulation [PDF]

open access: yes, 1964
A transistorized regulator converter efficiently converts fluctuating input voltages to a constant output voltage, avoiding the use of saturable reactors.

core   +1 more source

Design, Analysis, and Verification of a Decoupled Dual-Output Wireless Power Transfer System with a Constant Voltage Output and a Constant Current Output

open access: yesElectronics
Wireless power transfer (WPT) is extensively utilized because of its isolation and convenience. However, WPT systems require different types of outputs in specific applications. The existing dual-receiving WPT system has disadvantages such as redundant compensation components, unnecessary cross-coupling interference, complex control circuits, and low ...
Le Yu   +5 more
openaire   +1 more source

Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz   +3 more
wiley   +1 more source

High-Efficiency, Low-Power, Fully Integrated Neural Electrical Stimulation Circuit

open access: yesApplied Sciences
This paper presents a highly efficient, low-power, fully integrated neural stimulation circuit implemented using solely low-voltage devices. The circuit primarily consists of a high-voltage-generation circuit, an output driver circuit, and a constant ...
Yujiao Wang, Jiahao Cheong, Cheng Liu
doaj   +1 more source

Input-parallel–output-series control strategy for three-level medium-voltage DC grid-type converter

open access: yesThe Journal of Engineering, 2019
A control topology input-parallel–output-series converter system is investigated, which is suitable for high-voltage and high-output power applications.
Faisal Mehmood Shah   +6 more
doaj   +1 more source

Control for nuclear thermionic power source [PDF]

open access: yes, 1978
A control for a power source which includes nuclear fuel interspersed with thermionic converters, is described. A power regulator maintains a substantially constant output voltage to a variable load, and a control circuit drives a neutron flux regulator ...
Sawyer, C. D.
core   +1 more source

Normal‐Appearing White Matter Injury Mediates Chronic Deep Venous Hypoxia and Disease Progression in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang   +8 more
wiley   +1 more source

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