Results 41 to 50 of about 10,462,770 (299)
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Granular behaviour under bi-directional shear with constant vertical stress and constant volume
Journal of Rock Mechanics and Geotechnical EngineeringThis paper aims to investigate the role of bi-directional shear in the mechanical behaviour of granular materials and macro-micro relations by conducting experiments and discrete element method (DEM) modelling.
Min Zhang +3 more
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
On the real linear polarization constant problem [PDF]
, 2006 The present paper deals with lower bounds for the norm of products of linear forms. It has been proved by J. Arias-de-Reyna [2], that the so-called n(th) linear polarization constant c(n)(C-n) is n(n/2), for arbitrary n is an element of N. The same value
Matolcsi, Máté +3 more
core +2 more sources
Optimisation of constant matrix multiplication operation hardware using a genetic algorithm [PDF]
, 2006 The efficient design of multiplierless implementations of constant matrix multipliers is challenged by the huge solution search spaces even for small scale problems.
O'Connor, Noel E. +6 more
core +2 more sources
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Small Volume Bodies of Constant Width
International Mathematics Research NoticesAbstract For every large enough $n$, we explicitly construct a body of constant width $2$ that has volume less than $0.9^{n} \textrm{Vol}(\mathbb{B}^{n}$), where ${{\mathbb{B}}}^{n}$ is the unit ball in $\mathbb{R}^{n}$. This answers a question of O. Schramm.
Arman, Andrii +4 more
openaire +3 more sources
The Constant Volume Gas Thermometer [PDF]
Journal of Mathematics and Physics, 1922 n ...
openaire +1 more source