Results 61 to 70 of about 10,462,770 (299)

Design and Research of a High-Pressure-Resistant Constant Volume Combustion Device

open access: yesApplied Sciences
In response to the current limitation where conventional constant volume combustion apparatuses are generally confined to pressure ratings of 5–20 MPa, insufficient for the demands of ultra-high-pressure combustion fundamental research, this study ...
Qingmiao Ma   +6 more
doaj   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Topological properties of asymptotic invariants and universal volume bounds [PDF]

open access: yes, 2008
In this thesis, we prove that many asymptotic invariants of closed manifolds depend only on the image of the fundamental class under the classifying map of the universal covering.
Brunnbauer, Michael
core   +1 more source

PRECS Student: Cassidy Constant

open access: yes, 2023
Cassidy Constant, a participant in the Phenotypic Plasticity Research Experience for Community College Students, discusses the experience and assigned ...
Constant, Cassidy
core  

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Investigation of Flame Characteristics of Ethanol-Gasoline Blends Combustion Using Constant Volume Chamber

open access: yesMATEC Web of Conferences, 2016
The stricter on emission legislation and growing demands for lower fuel consumption require significant efforts to improve combustion efficiency while satisfying the demand of emission quality.
Baddu Nuriati   +4 more
doaj   +1 more source

A Rapid Method for Measuring the Volume of a Large Cavity Using Averaged Absorption Cross Section

open access: yesIEEE Access, 2017
The rapid and accurate measurement of the volume of a large cavity is much in demand in practice, especially for a cavity of irregular shape. In this paper, a new method is proposed to measure the volume of a large cavity.
Zhihao Tian   +3 more
doaj   +1 more source

Constant Pressure and Constant Volume Direct Shear Tests on Reinforced Sand

open access: yesSoils and Foundations, 2000
ABSTRACT In order to investigate the deformation and strength characteristics of reinforced sand, a series of relatively large-inscale direct shear tests was performed. Phosphor bronze strips and sheets with different configurations were used as reinforcement to study the effects of the shape and dimensions of reinforcement.
QIU, JINYING   +2 more
openaire   +2 more sources

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

open access: yesMolecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas   +16 more
wiley   +1 more source

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