Results 61 to 70 of about 7,580,136 (353)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Volume change behavior of bentonite-sand mixture under constant suction condition

MATEC Web of Conferences, 2018
The unsaturated state of soil can raise many geotechnical problems upon wetting-drying cycles such as volume change resulting in collapse or swell, change in the shear strength, and change in the hydraulic conductivity.
Al-Badran Yasir, Schanz Tom
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Biophysical approaches for studying viral entry

FEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Construction and start up of a large-volume thermostat for dielectric-constant-gas-thermometry

, 2009
A liquid-bath thermostat with a volume of about 800 L was designed to provide a suitable thermal environment for a dielectric-constant gas thermometer (DCGT) in the range from the triple point of mercury to the melting point of gallium.
C. GAISER, B. FELLMUTH, Moro, Francesco, Gaiser, C., Fellmuth, B., Merlone, A., MERLONE, ANDREA, F. MORO, A. MERLONE, T. ZANDT, Zandt, T.   +10 more
core   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Preservation of sweet cherry by isochoric (constant volume) freezing

Innovative Food Science & Emerging Technologies, 2019
Due to the perishable nature of fruits and the importance of reducing food waste, an effective preservation technique is required to prolong the shelf life and maintain the physical and nutritional properties of seasonal fruits.
C. Bilbao‐Sainz, A. Sinrod, M. Powell-Palm, L. Dao, G. Takeoka, Tina Williams, D. Wood, G. Ukpai, J. Aruda, David F. Bridges, V. Wu, B. Rubinsky, T. Mchugh   +12 more
semanticscholar   +1 more source

On the real linear polarization constant problem

, 2006
The present paper deals with lower bounds for the norm of products of linear forms. It has been proved by J. Arias-de-Reyna [2], that the so-called n(th) linear polarization constant c(n)(C-n) is n(n/2), for arbitrary n is an element of N. The same value
Matolcsi, Máté, Munoz, G. A., Máté Matolcsi, Gustavo A. Muñoz   +3 more
core   +1 more source

Small Volume Bodies of Constant Width

International Mathematics Research Notices
Abstract For every large enough $n$, we explicitly construct a body of constant width $2$ that has volume less than $0.9^{n} \textrm{Vol}(\mathbb{B}^{n}$), where ${{\mathbb{B}}}^{n}$ is the unit ball in $\mathbb{R}^{n}$. This answers a question of O. Schramm.
Arman, Andrii, Bondarenko, Andriy, Nazarov, Fedor, Prymak, Andriy, Radchenko, Danylo   +4 more
openaire   +3 more sources

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source