Results 81 to 90 of about 7,580,136 (353)

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

The constant-volume heat capacities of gaseous perfluorocyclobutane and propylene [PDF]

open access: yes, 1960
The constant-volume heat capacities of gaseous perfluorocyclobutane and propylene have been measured over a considerable range of temperatures and densities with a new type of adiabatic calorimeter.
De Nevers, Noel, Martin, Joseph J.
core   +1 more source

Volume growth of submanifolds and the Cheeger isoperimetric constant [PDF]

open access: yesProceedings of the American Mathematical Society, 2013
We obtain an estimate of the Cheeger isoperimetric constant in terms of the volume growth for a properly immersed submanifold in a Riemannian manifold which possesses at least one pole and sectional curvature bounded from above.
Gimeno, Vicent, Palmer Andreu, Vicente
openaire   +4 more sources

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Constant Pressure and Constant Volume Direct Shear Tests on Reinforced Sand

open access: yesSoils and Foundations, 2000
ABSTRACT In order to investigate the deformation and strength characteristics of reinforced sand, a series of relatively large-inscale direct shear tests was performed. Phosphor bronze strips and sheets with different configurations were used as reinforcement to study the effects of the shape and dimensions of reinforcement.
QIU, JINYING   +2 more
openaire   +2 more sources

Thermodynamics and dynamics of a monoatomic glass former. Constant pressure and constant volume behavior [PDF]

open access: yesThe Journal of Chemical Physics, 2008
We report constant-volume and constant-pressure simulations of the thermodynamic and dynamic properties of the low-temperature liquid and crystalline phases of the modified Stillinger–Weber (SW) model. We have found an approximately linear temperature increase of the effective Gaussian width of the distribution of inherent structures. This effect comes
Kapko, Vitaliy   +2 more
openaire   +3 more sources

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Investigation of Flame Characteristics of Ethanol-Gasoline Blends Combustion Using Constant Volume Chamber

open access: yesMATEC Web of Conferences, 2016
The stricter on emission legislation and growing demands for lower fuel consumption require significant efforts to improve combustion efficiency while satisfying the demand of emission quality.
Baddu Nuriati   +4 more
doaj   +1 more source

A Rapid Method for Measuring the Volume of a Large Cavity Using Averaged Absorption Cross Section

open access: yesIEEE Access, 2017
The rapid and accurate measurement of the volume of a large cavity is much in demand in practice, especially for a cavity of irregular shape. In this paper, a new method is proposed to measure the volume of a large cavity.
Zhihao Tian   +3 more
doaj   +1 more source

Development of human monoclonal antibodies against TARM1 by yeast display

open access: yesFEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe   +5 more
wiley   +1 more source

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