Results 71 to 80 of about 623,839 (308)
Let \(\Omega\) be a simply connected domain in the extended complex plane. Suppose that \(\infty\in \Omega\) and denote by \(G\) the Green function of \(\Omega\) with pole at \(\infty\). Littlewood introduced the constant \[ \beta=\sup_\Omega\limsup_{r\to 0}\frac{\log {\roman length}\{z:G(z)=r\}}{\log (1/r)}. \] It was proved by \textit{L.
Beliaev, Dmitri, Smirnov, Stanislav
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An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Refinement of Protein Tertiary Structure by Using Spin-Spin Coupling Constants from Nuclear Magnetic Resonance Measurements [PDF]
Modelling protein structure seems a challenging enterprise because the number of structure parameters required ordinarily exceeds the amount of independent data points available from experimental observations. Expressing the predominant conformation of a
Schmidt, Jürgen M. +5 more
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The prospect of a time-dependent Higgs vacuum expectation value is examined within the standard model of electroweak interactions. It is shown that the classical equation of motion for the Higgs field admits a solution that is a doubly-periodic function of time.
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Charged structure constants from modularity
We derive a universal formula for the average heavy-heavy-light structure constants for 2d CFTs with non-vanishing u1 $$ \mathfrak{u}(1) $$ charge. The derivation utilizes the modular properties of one-point functions on the torus. Refinements in N=2 $$ \
Diptarka Das, Shouvik Datta, Sridip Pal
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Architecture of Allosteric Structure. Rate Equations, Rate Constants, and Equilibrium Constants for Reaction of: Hb4 with O2 and (HbO2)4 with Dithionate, in the Presence of 2,3-Bisphosphoglycerate [PDF]
Three unknown quantities are all that is required to describe the O2-equilibrium binding curve for fractional saturation of human hemoglobin in red blood cells, under standard conditions: Kα, the O2-binding constant of equivalent α-chains; KC, the ...
Samantha J., Doyle +2 more
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In this issue of The Journal of Physiology, Uebachs et al. (2006) report a seemingly simple observation: the rate of recovery from inactivation of CaV3 (T-type) calcium channels depends on the length of the depolarization that produced the inactivation. Why is this heretical? A basic principle of chemical kinetics is that rate constants are constant.
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AbstractI review the current state of determinations of the Hubble constant, which gives the length scale of the Universe by relating the expansion velocity of objects to their distance. There are two broad categories of measurements. The first uses individual astrophysical objects which have some property that allows their intrinsic luminosity or size
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Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source

