Results 71 to 80 of about 161,884 (244)

Functional Constipation in Pregnancy; Need to Furnish Some More Emphasis

Annals of Abbasi Shaheed Hospital and Karachi Medical & Dental College, 2019
Objectives: This study was conducted to determine the occurrence of  functional  constipation  in  ob- stetric population in our context and  to  explore  the  extent  to  which  pregnant  females  were  aware of the problem and their usual practices to
Shabnum Shamim, Amna Begum
doaj   +1 more source

Weaning from ketogenic diet therapy in children with epilepsy: Insights from a retrospective study

Epilepsia, EarlyView.
Abstract Objective This study was undertaken to describe weaning practices following ketogenic diet therapy (KDT) in children with epilepsy and to identify clinical factors associated with seizure exacerbation or antiseizure medication adjustments during or after weaning from KDT.
Noémie Donnard, Blandine Dozières‐Puyravel, Katia Geraldes, Céline Perrot, Virginie Quéméner, Estelle Goujon, Pierre Truchy, Hala Nasser, François‐Xavier Mauvais, Marion Danse, Stéphane Auvin   +10 more
wiley   +1 more source

Negative association between body roundness index and constipation: insights from NHANES

Journal of Health, Population and Nutrition
Backgrounds The relationship between body roundness index (BRI), a metric that distinguishes heterogeneity in fat distribution, and constipation is unclear.
Lingting Chen, Huirong Xiao, Xuchao Yu, Bingbin Huang, Sirong Guo, Ting Yuan, Siyang Deng   +6 more
doaj   +1 more source

Stiripentol: Unpublished results from the first phase 2 clinical trial in Lennox–Gastaut syndrome conducted in the early 1990s

Epilepsia, EarlyView.
Abstract Objective This study was undertaken to present the results of an exploratory phase 2 trial of stiripentol in Lennox–Gastaut syndrome (LGS). Methods This exploratory single‐blind, single‐arm, nonrandomized sequential‐period phase 2 study was conducted at four centers in France between January 1989 and August 1993.
Stéphane Auvin, Benjamin Serraz, Jérémie Lespinasse, Laurent Chancharme   +3 more
wiley   +1 more source

Soticlestat as an adjunctive therapy in children and young adults with Dravet syndrome

Epilepsia, EarlyView.
Overview of the phase 3 trial evaluating soticlestat as adjunctive therapy in children and young adults with Dravet syndrome. Abstract Objective This study evaluated the efficacy, safety, and tolerability of soticlestat as adjunctive therapy in children and young adults with Dravet syndrome (DS).
Joseph Sullivan, Kette Valente, Vicente Villanueva, Adam Strzelczyk, Rima Nabbout, Eiji Nakagawa, Yuehua Zhang, Marta Zolnowska, Yasir Khan, Cheng Dong, Samuel Hsiao, Sarah I. Sheikh, Philipp von Rosenstiel, Mahnaz Asgharnejad, Venkatesha Murthy   +14 more
wiley   +1 more source

A modern view of the problem of constipation

Лечащий Врач
Background. PA new chronomedical approach to the classification of one of the most common syndromes in modern medicine, the constipation syndrome, is presented. According to Robert Hegglin "сonstipation is the absence of defecation for 24 hours".
Konstantin A. Shemerovskii, Raisa K. Kantemirova, Pavel V. Seliverstov   +2 more
doaj   +1 more source

Obstructive Uropathy in a Child with Severe Chronic Constipation

Proceedings of Singapore Healthcare, 2012
Urinary symptoms are well-described in children with chronic constipation which include enuresis, urgency and recurrent urinary infections. Renal tract obstruction is a rare complication of severe chronic constipation. We describe a case of a 10-year-old
Veena Logarajah MBBS, MRCPCH, Kong Boo Phua MBBS, M Med (Paeds), FRACP, FAMS, FRCPE, FRCPCH, Te Lu Yap MBBS, FRCS (Glasgow), Christina Ong MBBS, FRCPCH   +3 more
doaj   +1 more source

Intestinal microbiome alterations in pediatric epilepsy: Implications for seizures and therapeutic approaches

Epilepsia Open, EarlyView.
Abstract The intestinal microbiome plays a pivotal role in maintaining host health through its involvement in gastrointestinal, immune, and central nervous system (CNS) functions. Recent evidence underscores the bidirectional communication between the microbiota, the gut, and the brain and the impact of this axis on neurological diseases, including ...
Teresa Ravizza, Greta Volpedo, Antonella Riva, Pasquale Striano, Annamaria Vezzani   +4 more
wiley   +1 more source

Spotlight commentary: Deprescribing in long‐term care facilities—Towards safer and smarter medication use in older adults

British Journal of Clinical Pharmacology, EarlyView.
Nataša Skočibušić, Igor Rubinić, Vera Vlahović‐Palčevski   +2 more
wiley   +1 more source

Highly purified cannabidiol (CBD) in CDKL5 deficiency disorder (CDD): Open‐label prospective study

Epilepsia Open, EarlyView.
Abstract Objective CDKL5 deficiency disorder (CDD) is an early‐onset developmental and epileptic encephalopathy characterized by frequent drug‐resistant seizures, cerebral visual impairment, motor dysfunction, and sleep and gastrointestinal disturbances.
Marco Perulli, Alessia De Gioia, Federica Ruggiero, Federica Ascione, Chiara Porto, Elisa Musto, Valentina Massaroni, Maria Picilli, Maria Luigia Gambardella, Michela Quintiliani, Ilaria Contaldo, Chiara Veredice, Domenica Immacolata Battaglia   +12 more
wiley   +1 more source