Results 121 to 130 of about 444,140 (312)

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

The U.S. Constitution a very short introduction

open access: yes, 2018
Though the U.S. Constitution was ratified in 1788, its impact on our lives is as recent as today's news. Claims and counterclaims about the constitutionality of governmental actions are a habit of American politics.
Bodenhamer, David J. 1947-
core  

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Ohio Constitution

open access: yes
Digital print of the first page of the 1802 Ohio Constitution. In November 1802, thirty-five delegates of the Ohio Constitutional Convention convened to draft a state constitution.

core  

The feeding of school children by the London County Council.

open access: yes, 1909
An address to the British Constitution Association at the Whitehall Rooms, on March 22nd, 1909.Mode of access ...
British Constitution Association.   +1 more
core  

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Constitution and government of Kansas.

open access: yes, 1889
"Boughton's new map of Kansas, revised and corrected": 1 folded leaf laid in."Constitution of the State of Kansas, adopted at Wyandotte, July 29, l859" : p.
Kansas. Constitution. 1889.
core  

Factors influencing cognitive function in Chinese elderly individuals: The role of traditional Chinese medicine in a large-scale cross-sectional study

open access: yesJournal of Traditional Chinese Medical Sciences
Objective: To identify key factors influencing cognitive function in the elderly, including traditional Chinese medicine (TCM) constitutional classification, and to rank their relative importance.
Houqin Li   +6 more
doaj   +1 more source

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