Results 1 to 10 of about 36,390 (302)

Eosinophils and childhood asthma [PDF]

Clinical and Experimental Pediatrics, 2021
Eosinophils are a type of granulocyte with eosinophilic granules in the cytoplasm that play an important role in allergic and parasitic diseases. Eosinophils are important in the pathogenesis of asthma, and many studies have examined the relationship ...
Bong Seok Choi
doaj   +4 more sources

Eosinophilic Asthma: Pathophysiology and Therapeutic Horizons [PDF]

Cells
Asthma is a prevalent chronic non-communicable disease, affecting approximately 300 million people worldwide. It is characterized by significant airway inflammation, hyperresponsiveness, obstruction, and remodeling.
Musaddique Hussain, Gang Liu
doaj   +3 more sources

PRevalence of the Eosinophilic Phenotype Among SeveRE asthma patients in Lebanon: results of the PREPARE study [PDF]

Allergy, Asthma & Clinical Immunology, 2023
Background The prevalence of eosinophilic asthma in Lebanon, one of the most severe phenotypes among severe asthma, is not known. This study aimed at determining the prevalence of the eosinophilic phenotype defined as an eosinophil count ≥ 300 cells/mm3 ...
Wajdi Abi Saleh, Zuhair Alameh, Zeina Aoun Bacha, Joudy Bahous, Pierre Bou Khalil, Zahia Chahine, Hassan Chami, Georges Dabar, Hassan Dheiny, Alfred Dib, Dany farhat, Carla Irani, Georges Juvelekian, Nadim Kanj, Bassam Mansour, Moussa Riachi, Mirna Waked, Mohamad Yassine, Carole Youakim, Salah Zeinedine, Fares Zaitoun   +20 more
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Aerodigestive evaluation in patients with eosinophilic asthma [PDF]

Respiratory Medicine Case Reports
We present two pediatric patients with severe uncontrolled asthma who underwent aerodigestive evaluation revealing eosinophilic asthma and eosinophilic esophageal inflammation.
Chloe Citron, Jessica Erkman, Mikhail Kazachkov, Anna Nowak-Wegrzyn, Deniz Kesebir   +4 more
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Severe eosinophilic bronchial asthma: new therapeutic options

Медицинский совет, 2018
Eosinophilic asthma is a common phenotype of severe asthma, occurring in at least half of patients. In recent years, there have been significant changes in the approaches to the treatment of severe bronchial asthma and, above all, eosinophilic asthma ...
N. M. Nenasheva
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The Comparative Effectiveness of Mepolizumab and Benralizumab in the Treatment of Eosinophilic Asthma [PDF]

Advances in Respiratory Medicine
Background: Severe asthma is associated with significant morbidity and risk of complications. Some patients, suffering from eosinophilic asthma, may benefit from biological therapies, especially anti IL-5 (anti-interleukin-5).
Aleksandra Niemiec-Górska, Olga Branicka, Paula Olszewska, Sylwia Mielcarska, Joanna Glück, Barbara Rymarczyk, Radosław Gawlik   +6 more
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Classification of non-acute bronchial asthma according to allergy and eosinophil characteristics: a retrospective study

Allergy, Asthma & Clinical Immunology, 2021
Background Investigating the endotypes of the different asthma phenotypes would help disease monitoring, prognosis determination, and improving asthma management standardization.
Yi Jiang, Ruoli An, Li Cheng, Qianru Yue, Hanwei Zhang, Yali Zhang, Xiaomei Kong, Hongxia Ma, Fang Chen, Yufeng Guo   +9 more
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Two years follow-up of relapsing eosinophilic pneumonia with concomitant severe asthma successfully treated with benralizumab: A case report and brief review of the literature

Respiratory Medicine Case Reports, 2023
Relapsing eosinophilic pneumonia and severe eosinophilic asthma are rare and disabling diseases, which share common inflammatory backgrounds and often require long-term systemic steroid therapy.
G. Angeletti, M. Mazzolini, A. Rocca
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Identifying clinical and demographic characteristic differences between eosinophilic and non-eosinophilic asthma and detecting predictors of eosinophilic asthma among Egyptian asthmatic patients

The Egyptian Journal of Bronchology, 2022
Introduction Asthma is a heterogenous disease with various phenotypes that is characterized by airway limitation due to bronchospasm and airway inflammation associated with excessive mucus secretion.
Maged Mohamed Refaat, Riham Hazem Raafat, Heba Eid AbuAlia, Dina Sayed Sheha   +3 more
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Construction of Severe Eosinophilic Asthma Related Competing Endogenous RNA Network by Weighted Gene Co-Expression Network Analysis

Frontiers in Pharmacology, 2022
Background: Currently, disease control in patients with severe eosinophilic asthma is not optimistic. Competing endogenous RNA (ceRNA) networks have been found to play a key role in asthma in recent years.
Haixia Wang, Zeyi Zhang, Yu Ma, Yuanmin Jia, Bin Ma, Junlian Gu, Ou Chen, Ou Chen, Shouwei Yue, Shouwei Yue   +9 more
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