Results 21 to 30 of about 276,902 (250)

Classification of non-acute bronchial asthma according to allergy and eosinophil characteristics: a retrospective study

Allergy, Asthma & Clinical Immunology, 2021
Background Investigating the endotypes of the different asthma phenotypes would help disease monitoring, prognosis determination, and improving asthma management standardization.
Yi Jiang, Ruoli An, Li Cheng, Qianru Yue, Hanwei Zhang, Yali Zhang, Xiaomei Kong, Hongxia Ma, Fang Chen, Yufeng Guo   +9 more
doaj   +1 more source

Two years follow-up of relapsing eosinophilic pneumonia with concomitant severe asthma successfully treated with benralizumab: A case report and brief review of the literature

Respiratory Medicine Case Reports, 2023
Relapsing eosinophilic pneumonia and severe eosinophilic asthma are rare and disabling diseases, which share common inflammatory backgrounds and often require long-term systemic steroid therapy.
G. Angeletti, M. Mazzolini, A. Rocca
doaj   +1 more source

Identifying clinical and demographic characteristic differences between eosinophilic and non-eosinophilic asthma and detecting predictors of eosinophilic asthma among Egyptian asthmatic patients

The Egyptian Journal of Bronchology, 2022
Introduction Asthma is a heterogenous disease with various phenotypes that is characterized by airway limitation due to bronchospasm and airway inflammation associated with excessive mucus secretion.
Maged Mohamed Refaat, Riham Hazem Raafat, Heba Eid AbuAlia, Dina Sayed Sheha   +3 more
doaj   +1 more source

Construction of Severe Eosinophilic Asthma Related Competing Endogenous RNA Network by Weighted Gene Co-Expression Network Analysis

Frontiers in Pharmacology, 2022
Background: Currently, disease control in patients with severe eosinophilic asthma is not optimistic. Competing endogenous RNA (ceRNA) networks have been found to play a key role in asthma in recent years.
Haixia Wang, Zeyi Zhang, Yu Ma, Yuanmin Jia, Bin Ma, Junlian Gu, Ou Chen, Ou Chen, Shouwei Yue, Shouwei Yue   +9 more
doaj   +1 more source

Characteristics of patients with asthma overprescribed short-acting beta-agonist (SABA) reliever inhalers stratified by blood eosinophil count in North East London: a cross-sectional observational study

BJGP Open, 2023
Background: Overprescription of short-acting beta-agonist (SABA) inhalers and blood eosinophil count have strong associations with exacerbation risk in asthma.
Paul Pfeffer, Hajar Hajmohammadi, James Cole, Chris Griffiths, Sally Hull, Anna De Simoni   +5 more
doaj   +1 more source

Macrophage and dendritic cell subset composition can distinguish endotypes in adjuvant-induced asthma mouse models.

PLoS ONE, 2021
Asthma is a heterogeneous disease with neutrophilic and eosinophilic asthma as the main endotypes that are distinguished according to the cells recruited to the airways and the related pathology.
Müge Özkan, Yusuf Cem Eskiocak, Gerhard Wingender   +2 more
doaj   +1 more source

Neutrophils and Asthma

Diagnostics, 2022
Although eosinophilic inflammation is characteristic of asthma pathogenesis, neutrophilic inflammation is also marked, and eosinophils and neutrophils can coexist in some cases. Based on the proportion of sputum cell differentiation, asthma is classified
Akira Yamasaki, Ryota Okazaki, Tomoya Harada   +2 more
doaj   +1 more source

Eosinophilic inflammation: An Appealing Target for Pharmacologic Treatments in Severe Asthma

Biomedicines, 2022
Severe asthma is characterized by different endotypes driven by complex pathologic mechanisms. In most patients with both allergic and non-allergic asthma, predominant eosinophilic airway inflammation is present.
Alessandro Vatrella, Angelantonio Maglio, Corrado Pelaia, Luigi Ciampo, Giulia Pelaia, Carolina Vitale   +5 more
doaj   +1 more source

Experience with mepolizumab in adults with severe eosinophilic asthma: a case series from India

Respirology Case Reports, 2021
Severe asthma can be associated with eosinophilic or allergic phenotypes or both. Eosinophilic inflammation is associated with exacerbations and disease severity due to biological activity of interleukin‐5 (IL‐5).
Venkata Nagarjuna Maturu, Priti Meshram, Soumya Das, Ashok Kumar Rajput, Arun Chowdary Kotaru, Bhavesh Kotak, Neeraj Markandeywar, Simran Chhatwal   +7 more
doaj   +1 more source

A Case of Eosinophilic Gastroenteritis Remission Achieved Steroid-Free With Mepolizumab

Gastro Hep Advances, 2022
Eosinophilic gastroenteritis is an eosinophilic inflammatory disease that responds well to steroids but often relapses upon their discontinuation, necessitating maintenance treatment.
Yuki Hirata, Takahiko Nakamura, Kazuhide Higuchi   +2 more
doaj   +1 more source