Results 21 to 30 of about 31,457 (263)
Fasting impairs type 2 helper T cell infiltration in the lung of an eosinophilic asthma mouse model
FEBS Open Bio, 2021 Eosinophilic asthma is a form of bronchial asthma that is caused by the pulmonary infiltration of eosinophils and accounts for approximately half of the patients with severe asthma.
Yusuke Suzuki +7 more
doaj +1 more source
Update on reslizumab for eosinophilic asthma [PDF]
Expert Opinion on Biological Therapy, 2015 Patients with severe eosinophilic asthma have an unmet need for novel and efficacious treatments. Reslizumab is one of the three monoclonal antibodies targeting the IL-5 pathway and has been found in Phase IIIb clinical trials to reduce asthma exacerbations, control asthma-related symptoms and improve pulmonary function in patients with eosinophilic ...
Cardet, Juan Carlos, Israel, Elliot
openaire +4 more sources
Utility of serum periostin in combination with exhaled nitric oxide in the management of asthma
Allergology International, 2017 Type-2/eosinophilic inflammation plays a pivotal role in asthma. The identification of severe type-2/eosinophilic asthma is important for improving the management of patients with asthma.
Tadao Nagasaki +19 more
doaj +1 more source
Asthma control and sputum eosinophils in adult patients: a cross-sectional study in southern Brazil
Scientific Reports, 2023 Asthma control and health related quality of life are an important goal of asthma management, but their association with sputum eosinophilic inflammation has been less firmly established.
Vanessa Albano Barcellos +3 more
doaj +1 more source
Development of eosinophilic pneumonia from eosinophilic bronchiolitis without asthma: A case report
Respiratory Medicine Case Reports, 2023 Eosinophilic bronchiolitis is a disease concept reported in Japan in 2001, that presents with bronchiolitis accompanied by eosinophilia in the blood and lungs.
Erika Mikami +8 more
doaj +1 more source
BMC Pulmonary Medicine, 2022 Background Eosinophilia is a significant factor in asthma severity; however, the prevalence of severe eosinophilic asthma in Saudi Arabia is largely unknown.
Hamdan Al-Jahdali +6 more
doaj +1 more source
Frontiers in Pharmacology, 2022 The pathogenesis of allergic asthma is complex, it is usually caused by immune system imbalance. Th1, Th2, regulatory T cells (Treg) and T helper 17 (Th17) cells have an important role in the pathogenesis of eosinophilic asthma.
Yumei Zhou +4 more
doaj +1 more source
The cough variant asthma [PDF]
Терапевтический архив, 2020 Cough variant asthma (CVA) was first described by W. Corrao. CVA was described as the isolated chronic cough as the only presenting symptom responsive to bronchodilator therapy.This phenotype of asthma is present with airway hyperresponsiveness ...
M. O. Uryasjev +3 more
doaj +1 more source
Frontiers in Pharmacology, 2021 Background: Severe eosinophilic asthma decreases lung function and causes worsen symptoms, often forcing recurrent maintenance corticosteroid use. The aim of our real-life study was to evaluate the effectiveness of an add-on treatment with benralizumab ...
Giulia Scioscia +14 more
doaj +1 more source
Targeting eosinophils: severe asthma and beyond
Drugs in Context, 2019 Recent research in the field of bronchial asthma has mainly focused on eosinophilic disease phenotype. Several trials proved the efficacy and safety profile of eosinophils and interleukin (IL)-5 targeting molecules, currently approved for severe asthma ...
Marco, Francesco, Lucia, Gianenrico
doaj +1 more source