Results 21 to 30 of about 51,921 (307)
BJGP Open, 2023 Background: Overprescription of short-acting beta-agonist (SABA) inhalers and blood eosinophil count have strong associations with exacerbation risk in asthma.
Paul Pfeffer +5 more
doaj +1 more source
PLoS ONE, 2021 Asthma is a heterogeneous disease with neutrophilic and eosinophilic asthma as the main endotypes that are distinguished according to the cells recruited to the airways and the related pathology.
Müge Özkan +2 more
doaj +1 more source
Diagnostics, 2022 Although eosinophilic inflammation is characteristic of asthma pathogenesis, neutrophilic inflammation is also marked, and eosinophils and neutrophils can coexist in some cases. Based on the proportion of sputum cell differentiation, asthma is classified
Akira Yamasaki +2 more
doaj +1 more source
Thorax, 2021 A man in his 30s, with a history of mild childhood asthma only, went to his local hospital with difficulty in breathing. His presentation was preceded by 6 days of worsening breathlessness, wheeze and cough. He had been using his mother’s salbutamol inhaler and received oral amoxicillin in the community.
McLellan, Tom +5 more
openaire +3 more sources
Targeting Eosinophils in Asthma [PDF]
Current Molecular Medicine, 2008 Recruitment of eosinophils has long been recognized as a hallmark of the inflammatory response in asthma. However, the functions of this population of cells in host defense remain poorly understood. Eosinophils play an important part in the inflammatory response and have key regulatory roles in the afferent arm of the immune response.
Foster, Paul S. +3 more
openaire +2 more sources
Eosinophilic inflammation: An Appealing Target for Pharmacologic Treatments in Severe Asthma
Biomedicines, 2022 Severe asthma is characterized by different endotypes driven by complex pathologic mechanisms. In most patients with both allergic and non-allergic asthma, predominant eosinophilic airway inflammation is present.
Alessandro Vatrella +5 more
doaj +1 more source
Experience with mepolizumab in adults with severe eosinophilic asthma: a case series from India
Respirology Case Reports, 2021 Severe asthma can be associated with eosinophilic or allergic phenotypes or both. Eosinophilic inflammation is associated with exacerbations and disease severity due to biological activity of interleukin‐5 (IL‐5).
Venkata Nagarjuna Maturu +7 more
doaj +1 more source
A Case of Eosinophilic Gastroenteritis Remission Achieved Steroid-Free With Mepolizumab
Gastro Hep Advances, 2022 Eosinophilic gastroenteritis is an eosinophilic inflammatory disease that responds well to steroids but often relapses upon their discontinuation, necessitating maintenance treatment.
Yuki Hirata +2 more
doaj +1 more source
Is there a rationale and role for long-acting anticholinergic bronchodilators in asthma? [PDF]
, 2014 The authors acknowledge the medical writing assistance received from Sam Yarwood, PhD, of Complete HealthVizion, in the form of literature searches and preparation and revision of the draft manuscript.Peer reviewedPublisher ...
Fromer, Leonard +4 more
core +15 more sources
Eosinophilic Inflammation in Allergic Asthma [PDF]
Frontiers in Pharmacology, 2013 Eosinophils are circulating granulocytes involved in pathogenesis of asthma. A cascade of processes directed by Th2 cytokine producing T-cells influence the recruitment of eosinophils into the lungs. Furthermore, multiple elements including interleukin (IL)-5, IL-13, chemoattractants such as eotaxin, Clara cells, and CC chemokine receptor (CCR)3 are ...
Possa, Samantha S. +4 more
openaire +4 more sources