Severe eosinophilic bronchial asthma: new therapeutic options [PDF]
Медицинский совет, 2018 Eosinophilic asthma is a common phenotype of severe asthma, occurring in at least half of patients. In recent years, there have been significant changes in the approaches to the treatment of severe bronchial asthma and, above all, eosinophilic asthma ...
N. M. Nenasheva
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15-hydroxyeicosatetraenoic acid (15-HETE)-GPR39 axis: a potential therapeutic target in eosinophilic asthma [PDF]
Frontiers in PharmacologyArachidonic acid (AA) metabolites play key roles in the pathophysiology of asthma. Along with cyclooxygenase and CYP P450, lipoxygenases (LO) produce these metabolites. 15-hydroxyeicosatetraenoic acid (15-HETE), a product of 15-LO, has been implicated in
Andrew Engel, Zhenying Nie, Sanjiv Kaul
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Clinical characteristics of eosinophilic COPD versus COPD patients with a history of asthma [PDF]
Respiratory Research, 2017 Eosinophilic COPD appears to be a distinct patient subgroup with an increased corticosteroid response. Eosinophilic COPD has been labelled as part of the asthma COPD overlap syndrome (ACOS).
Umme Kolsum +5 more
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Development of eosinophilic pneumonia from eosinophilic bronchiolitis without asthma: A case report
Respiratory Medicine Case Reports, 2023 Eosinophilic bronchiolitis is a disease concept reported in Japan in 2001, that presents with bronchiolitis accompanied by eosinophilia in the blood and lungs.
Erika Mikami +8 more
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Aerodigestive evaluation in patients with eosinophilic asthma [PDF]
Respiratory Medicine Case ReportsWe present two pediatric patients with severe uncontrolled asthma who underwent aerodigestive evaluation revealing eosinophilic asthma and eosinophilic esophageal inflammation.
Chloe Citron +4 more
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The identification of eosinophilic gastroenteritis in prednisone-dependent eosinophilic bronchitis and asthma [PDF]
Allergy, Asthma & Clinical Immunology, 2011 This case reports the unique association of eosinophilic gastrointestinal disease with eosinophilic bronchitis, asthma and chronic rhinosinusitis and some features of lymphocytic hypereosinophilic syndrome, describes a diagnostic protocol for patients ...
Nair Parameswaran +5 more
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Cellular Mechanisms Underlying Eosinophilic and Neutrophilic Airway Inflammation in Asthma
Mediators of Inflammation, 2015 Asthma is a phenotypically heterogeneous chronic disease of the airways, characterized by either predominant eosinophilic or neutrophilic, or even mixed eosinophilic/neutrophilic inflammatory patterns. Eosinophilic inflammation can be associated with the
Girolamo Pelaia +6 more
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PRevalence of the Eosinophilic Phenotype Among SeveRE asthma patients in Lebanon: results of the PREPARE study [PDF]
Allergy, Asthma & Clinical Immunology, 2023 Background The prevalence of eosinophilic asthma in Lebanon, one of the most severe phenotypes among severe asthma, is not known. This study aimed at determining the prevalence of the eosinophilic phenotype defined as an eosinophil count ≥ 300 cells/mm3 ...
Wajdi Abi Saleh +20 more
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The Comparative Effectiveness of Mepolizumab and Benralizumab in the Treatment of Eosinophilic Asthma [PDF]
Advances in Respiratory MedicineBackground: Severe asthma is associated with significant morbidity and risk of complications. Some patients, suffering from eosinophilic asthma, may benefit from biological therapies, especially anti IL-5 (anti-interleukin-5).
Aleksandra Niemiec-Górska +6 more
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Eosinophils and childhood asthma [PDF]
Clinical and Experimental Pediatrics, 2021 Eosinophils are a type of granulocyte with eosinophilic granules in the cytoplasm that play an important role in allergic and parasitic diseases. Eosinophils are important in the pathogenesis of asthma, and many studies have examined the relationship ...
Bong Seok Choi
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