Results 11 to 20 of about 36,390 (302)

Eosinophilic bronchitis without asthma [PDF]

open access: yesInternational Archives of Allergy and Immunology, 2008
Background: Eosinophilic bronchitis without asthma causes chronic coughs without the physiologic features of asthma. The aim of this study was to review the clinical features, pathogenesis, diagnosis, treatment and prognosis of this condition.
Gonlugur, Ugur   +1 more
core   +4 more sources

Update on Reslizumab for Eosinophilic Asthma [PDF]

open access: yesExpert Opinion on Biological Therapy, 2021
Introduction Patients with severe eosinophilic asthma have an unmet need for novel and efficacious treatments. Reslizumab is one of three monoclonal antibodies targeting the interleukin-5 (IL5) pathway and has been found in phase 3b clinical trials to ...
Israel, Elliot, Cardet, Juan Carlos
core   +5 more sources

Severe Eosinophilic Asthma [PDF]

open access: yesJournal of Clinical Medicine, 2019
Asthma is a heterogeneous disease with varying severity. Severe asthma is a subject of constant research because it greatly affects patients’ quality of life, and patients with severe asthma experience symptoms, exacerbations, and medication side ...
Stelios Loukides   +5 more
core   +4 more sources

Improving the diagnosis of eosinophilic asthma [PDF]

open access: yesExpert Review of Respiratory Medicine, 2016
Diagnosing eosinophilic asthma is important, because uncontrolled eosinophilic airway inflammation is associated with reduced response to glucocorticoids and increased risk of severe exacerbations. Currently, the diagnosis of eosinophilic asthma is based
Bel, Elisabeth H., Coumou, Hanneke
core   +3 more sources

Characteristics of patients with asthma overprescribed short-acting beta-agonist (SABA) reliever inhalers stratified by blood eosinophil count in North East London: a cross-sectional observational study

open access: yesBJGP Open, 2023
Background: Overprescription of short-acting beta-agonist (SABA) inhalers and blood eosinophil count have strong associations with exacerbation risk in asthma.
Paul Pfeffer   +5 more
doaj   +1 more source

Asthma, ECMO and eosinophils

open access: yesThorax, 2021
A man in his 30s, with a history of mild childhood asthma only, went to his local hospital with difficulty in breathing. His presentation was preceded by 6 days of worsening breathlessness, wheeze and cough. He had been using his mother’s salbutamol inhaler and received oral amoxicillin in the community.
McLellan, Tom   +5 more
openaire   +3 more sources

Macrophage and dendritic cell subset composition can distinguish endotypes in adjuvant-induced asthma mouse models.

open access: yesPLoS ONE, 2021
Asthma is a heterogeneous disease with neutrophilic and eosinophilic asthma as the main endotypes that are distinguished according to the cells recruited to the airways and the related pathology.
Müge Özkan   +2 more
doaj   +1 more source

Neutrophils and Asthma

open access: yesDiagnostics, 2022
Although eosinophilic inflammation is characteristic of asthma pathogenesis, neutrophilic inflammation is also marked, and eosinophils and neutrophils can coexist in some cases. Based on the proportion of sputum cell differentiation, asthma is classified
Akira Yamasaki   +2 more
doaj   +1 more source

Dupilumab suppresses relapsing chronic eosinophilic pneumonia with severe asthma [PDF]

open access: yes, 2023
Dupilumab-induced hypereosinophilia is mediated by blockade of the IL-4/IL-13 pathway, which reduces eosinophil migration from peripheral blood. The increase in peripheral blood eosinophils may lead to chronic eosinophilic pneumonia (CEP) and/or ...
Motobayashi, Yuto   +7 more
core   +1 more source

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