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Methodological Aspects of Induced Sputum

Advances in Respiratory Medicine, 2023
We aimed to conduct a state-of-the-art review of the current literature and offer further insights into the methodological aspects concerning induced sputum.
Giovanna Elisiana Carpagnano, Simone Scarlata, András Bikov   +2 more
exaly   +3 more sources

Pulmonary tuberculosis in clinical practice

Сибирский научный медицинский журнал, 2021
Pulmonary tuberculosis has a lot of clinical manifestations, and it complicates the diagnosis of tuberculosis in the general clinical practice. We studied the clinical manifestations of tuberculosis detected in the pulmonary department and compared them ...
A. T. Shubina, E. A. Borodulina, A. N. Gerasimov, E. V. Yakovleva   +3 more
doaj   +1 more source

Nontuberculous mycobacteria isolation from sputum specimens: A retrospective analysis of 1061 cases

International Journal of Mycobacteriology, 2023
Background: In recent years, with the development of laboratory methods, the frequency of nontuberculosis mycobacteria (NTM) infections has increased. The primary aim of this study was to evaluate the clinical significance of therapeutic drug monitoring (
Aylin Babalik, Emine Nur Koç, Hamide Gül Sekerbey, Gül Erdal Dönmez, Ahmet Balikçi, Zeki Kiliçaslan   +5 more
doaj   +1 more source

Specific associations between fungi and bacteria in broncho-alveolar aspirates from mechanically ventilated intensive care unit patients

Virulence, 2022
The detection of fungi in the human respiratory tract may represent contamination, colonization or a respiratory infection. To develop effective management strategies, a more accurate and comprehensive understanding of the lung fungal microbiome is ...
Arezoo Shajiei, Lei Liu, Jolien Seinen, Willem Dieperink, Sven Hammerschmidt, Jan Maarten van Dijl, Hermie J.M. Harmsen   +6 more
doaj   +1 more source

An Innovative Protocol for Metaproteomic Analyses of Microbial Pathogens in Cystic Fibrosis Sputum

Frontiers in Cellular and Infection Microbiology, 2021
Hallmarks of cystic fibrosis (CF) are increased viscosity of mucus and impaired mucociliary clearance within the airways due to mutations of the cystic fibrosis conductance regulator gene.
Alexander C. Graf, Johanna Striesow, Jan Pané-Farré, Thomas Sura, Martina Wurster, Michael Lalk, Dietmar H. Pieper, Dörte Becher, Barbara C. Kahl, Katharina Riedel   +9 more
doaj   +1 more source

Common bacteria in sputum or gastric lavage of patients presenting with signs and symptoms of lower respiratory tract infections

The Pan African Medical Journal, 2021
INTRODUCTION: Lower respiratory tract infections (LRTIs) are infections involving the trachea, primary bronchi and lungs. People with LRTIs typically experience coughs as the primary symptoms; however, shortness of breath, weakness, fever and fatigue may
Oliver Deberu, Bernard Nkrumah, Augustina Angelina Sylverken, David Sambian, Godfred Acheampong, John Amuasi, Azure Stebleson, Daron Agboyie, Monica Yenbaree, Sylvester Mensah, Abaifa Dombadoh, Dorcas Ohui Owusu, Abass Abdul-Karim, Michael Owusu   +13 more
doaj   +1 more source

Mapping bacterial diversity and metabolic functionality of the human respiratory tract microbiome

Journal of Oral Microbiology, 2022
Background The Human Respiratory Tract (HRT) is colonized by various microbial taxa, known as HRT microbiota, in a manner that is indicative of mutualistic interaction between such microorganisms and their host.Aim To investigate the microbial ...
Leonardo Mancabelli, Christian Milani, Federico Fontana, Gabriele Andrea Lugli, Chiara Tarracchini, Francesca Turroni, Douwe van Sinderen, Marco Ventura   +7 more
doaj   +1 more source

Quick and wide-range taxonomical repertoire establishment of the cystic fibrosis lung microbiota by tandem mass spectrometry on sputum samples

Frontiers in Microbiology, 2022
Microorganisms proteotyping by tandem mass spectrometry has been recently shown as a powerful methodology to identify the wide-range taxonomy and biomass of microbiota.
Pauline Hardouin, Pauline Hardouin, Olivier Pible, Hélène Marchandin, Karen Culotta, Jean Armengaud, Raphaël Chiron, Lucia Grenga   +7 more
doaj   +1 more source

Gram Stain and Culture of Sputum Samples Detect Only Few Pathogens in Community-Acquired Lower Respiratory Tract Infections: Secondary Analysis of a Randomized Controlled Trial

Diagnostics, 2023
Identification of the bacterial etiology of lower respiratory tract infections (LRTI) is crucial to ensure a narrow-spectrum, targeted antibiotic treatment.
Mariana B. Cartuliares, Helene Skjøt-Arkil, Christian B. Mogensen, Thor A. Skovsted, Steen L. Andersen, Andreas K. Pedersen, Flemming S. Rosenvinge   +6 more
doaj   +1 more source

Role and Significance of Bioactive Substances in Sputum
 in the Diagnosis of Lung Cancer

Chinese Journal of Lung Cancer, 2021
The incidence rate of lung cancer is one of the highest incidence of malignancies in China. The gold standard for diagnosis requires pathological examination or cytological examination of biopsy.
Yuming JIN, Zixuan CHEN, Quan CHEN, Leihao SHA, Cheng SHEN   +4 more
doaj   +1 more source