Results 1 to 10 of about 255,935 (312)

Detection and Analysis of Microplastics in Human Sputum

Environmental Science & Technology, 2022
Microplastic pollution is an emerging environmental problem, and little research has focused on its impact on the human body. Based on retrospective case series, the study required participants to fill out a questionnaire and provide sputum samples in ...
Ran Bi, Pi Guo, Haisheng Wu
exaly   +2 more sources

Sputum IgE and Cytokines in Asthma: Relationship with Sputum Cellular Profile

PLoS ONE, 2013
Local IgE production may play a role in asthma pathogenesis. The aim of the study was to assess sputum total IgE and cytokines in asthmatics according to sputum cellular phenotype.We studied 122 subjects including 22 non atopic healthy subjects, 41 eosinophilic (sputum eosinophils ≥3%), 16 neutrophilic (sputum neutrophils >76%) and 43 pauci ...
Florence Schleich, Claus Bachert, Renaud Louis   +2 more
exaly   +5 more sources

Pharmacologic improvement of CFTR function rapidly decreases sputum pathogen density, but lung infections generally persist

Journal of Clinical Investigation, 2023
Background Lung infections are among the most consequential manifestations of cystic fibrosis (CF) and are associated with reduced lung function and shortened survival.
D. Nichols, Sarah J. Morgan, M. Skalland, A. Vo, J. V. Van Dalfsen, Sachinkumar Singh, W. Ni, L. Hoffman, Kailee McGeer, S. Heltshe, J. Clancy, S. Rowe, Peter A. Jorth, Pradeep K. Singh   +13 more
semanticscholar   +1 more source

Pulmonary tuberculosis in clinical practice

Сибирский научный медицинский журнал, 2021
Pulmonary tuberculosis has a lot of clinical manifestations, and it complicates the diagnosis of tuberculosis in the general clinical practice. We studied the clinical manifestations of tuberculosis detected in the pulmonary department and compared them ...
A. T. Shubina, E. A. Borodulina, A. N. Gerasimov, E. V. Yakovleva   +3 more
doaj   +1 more source

Pseudomonas aeruginosa aggregates in cystic fibrosis sputum produce exopolysaccharides that likely impede current therapies

Cell Reports, 2021
SUMMARY In cystic fibrosis (CF) airways, Pseudomonas aeruginosa forms cellular aggregates called biofilms that are thought to contribute to chronic infection. To form aggregates, P.
Laura K. Jennings, Julia E. Dreifus, Courtney Reichhardt, K. M. Storek, P. Secor, D. Wozniak, K. Hisert, M. Parsek   +7 more
semanticscholar   +1 more source

Nontuberculous mycobacteria isolation from sputum specimens: A retrospective analysis of 1061 cases

International Journal of Mycobacteriology, 2023
Background: In recent years, with the development of laboratory methods, the frequency of nontuberculosis mycobacteria (NTM) infections has increased. The primary aim of this study was to evaluate the clinical significance of therapeutic drug monitoring (
Aylin Babalik, Emine Nur Koç, Hamide Gül Sekerbey, Gül Erdal Dönmez, Ahmet Balikçi, Zeki Kiliçaslan   +5 more
doaj   +1 more source

Essential genome of Pseudomonas aeruginosa in cystic fibrosis sputum

Proceedings of the National Academy of Sciences of the United States of America, 2015
Marvin Whiteley, Aimee K Wessel, Whiteley Marvin   +2 more
exaly   +2 more sources

COVID-19–related Genes in Sputum Cells in Asthma. Relationship to Demographic Features and Corticosteroids

American Journal of Respiratory and Critical Care Medicine, 2020
Rationale: Coronavirus disease (COVID-19) is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). ACE2 (angiotensin-converting enzyme 2), and TMPRSS2 (transmembrane protease serine 2) mediate viral infection of host cells.
M. Peters, S. Sajuthi, P. DeFord, S. Christenson, C. Rios, M. Montgomery, P. Woodruff, D. Mauger, S. Erzurum, M. Johansson, Loren C. Denlinger, N. Jarjour, M. Castro, A. Hastie, W. Moore, V. Ortega, E. Bleecker, S. Wenzel, E. Israel, B. Levy, M. Seibold, J. Fahy   +21 more
semanticscholar   +1 more source

Specific associations between fungi and bacteria in broncho-alveolar aspirates from mechanically ventilated intensive care unit patients

Virulence, 2022
The detection of fungi in the human respiratory tract may represent contamination, colonization or a respiratory infection. To develop effective management strategies, a more accurate and comprehensive understanding of the lung fungal microbiome is ...
Arezoo Shajiei, Lei Liu, Jolien Seinen, Willem Dieperink, Sven Hammerschmidt, Jan Maarten van Dijl, Hermie J.M. Harmsen   +6 more
doaj   +1 more source

SARS-CoV-2–Positive Sputum and Feces After Conversion of Pharyngeal Samples in Patients With COVID-19

Annals of Internal Medicine, 2020
SARS-CoV-2–Positive Sputum and Feces After Conversion of Pharyngeal Samples in Patients With COVID-19 Background: The outbreak of coronavirus disease 2019 (COVID-19) has become a global public health problem.
Chen Chen, Gui-ju Gao, Yanli Xu, L. Pu, Qi Wang, Liming Wang, Wenling Wang, Yangzi Song, Meiling Chen, Linghang Wang, Feng-ting Yu, Siyuan Yang, Yun-xia Tang, Li Zhao, Huijuan Wang, Yajie Wang, H. Zeng, Fujie Zhang   +17 more
semanticscholar   +1 more source