Results 41 to 50 of about 255,935 (312)

Sputum exosomes: promising biomarkers for idiopathic pulmonary fibrosis

open access: yesThorax, 2018
Idiopathic pulmonary fibrosis (IPF) is a progressive fibrosing interstitial lung disease of unknown aetiology which leads rapidly to death. As diagnosis of IPF is complex, we aimed to characterise microRNA (miRNA) content of exosomes from sputum of ...
Makon-Sébastien NJOCK   +8 more
semanticscholar   +1 more source

Update on sputum methodology [PDF]

open access: yesEuropean Respiratory Journal, 2000
Over the past few years cellular and biochemical sputum examinations have become important instruments to assess airway inflammation. The aim of this review is to summarize new methodological developments and aspects, which are currently under investigation.
O, Holz, J, Kips, H, Magnussen
openaire   +2 more sources

Parasitic necrotizing pneumonia in an immunocompetent patient in United States

open access: yesJournal of Community Hospital Internal Medicine Perspectives, 2021
A 59-year-old Baltimore native female, with a history of asthma and no history of travel outside of the USA, presented with productive cough and shortness of breath.
Harish Gopalakrishna   +2 more
doaj   +1 more source

The CF-Sputum Induction Trial (CF-SpIT) to assess lower airway bacterial sampling in young children with cystic fibrosis: a prospective internally controlled interventional trial

open access: yesThe Lancet Respiratory Medicine, 2018
Summary Background Pathogen surveillance is challenging but crucial in children with cystic fibrosis—who are often non-productive of sputum even if actively coughing—because infection and lung disease begin early in life.
K. Ronchetti   +7 more
semanticscholar   +1 more source

Neutrophil count in sputum is associated with increased sputum glucose and sputum L-lactate in cystic fibrosis

open access: yesPLOS ONE, 2020
Markers of lung inflammation measured directly in expectorated sputum have the potential of improving the timing of antibiotic treatment in cystic fibrosis (CF). L-Lactate might be a marker of inflammation, as it is produced from glucose by polymorphonuclear neutrophils (PMNs) in CF lungs.
Bibi Uhre Nielsen   +7 more
openaire   +5 more sources

CD177 Deficiency Defines a Stable Subtype of Human Neutrophil Granulocytes with Tumor Promoting Activity

open access: yesAdvanced Science, EarlyView.
Human neutrophils exist as two epigenetically imprinted subtypes defined by stable CD177 expression or absence — a ratio that persists across time, circadian rhythms, and inflammation. CD177− neutrophils display a distinct molecular landscape enriched in arginase 1 and lipid metabolism markers, accumulate in head‐and‐neck tumors, and associate with ...
Marcel Jung   +39 more
wiley   +1 more source

Influence of Stress and Antibiotic Resistance on Cell-Length Distribution in Mycobacterium tuberculosis Clinical Isolates

open access: yesFrontiers in Microbiology, 2017
Mycobacterial cellular variations in growth and division increase heterogeneity in cell length, possibly contributing to cell-to-cell variation in host and antibiotic stress tolerance. This may be one of the factors influencing Mycobacterium tuberculosis
Srinivasan Vijay   +17 more
doaj   +1 more source

Au nanorod assembly for sensitive SERS detection of airway inflammatory factors in sputum

open access: yesFrontiers in Bioengineering and Biotechnology, 2023
In this paper, we demonstrate a surface-enhanced Raman spectroscopy (SERS) biosensor based on the self-assembly of gold nanorods (AuNRs) for the specific detection of airway inflammatory factors in diluted sputum.
An-qi Yang   +7 more
doaj   +1 more source

Blood and sputum eosinophils in COPD; relationship with bacterial load

open access: yesRespiratory Research, 2017
BackgroundSputum and blood eosinophil counts predict corticosteroid effects in COPD patients. Bacterial infection causes increased airway neutrophilic inflammation.
U. Kolsum   +12 more
semanticscholar   +1 more source

A Comprehensive Microbial Gene Catalog of the Human Airway Microbiome Across Anatomical Sites and Geographic Regions

open access: yesAdvanced Science, EarlyView.
An integrated Human Airway Microbiome Gene Catalog (iHAMGC) is constructed from 12,273 metagenomic airway samples, providing a high‐resolution reference of respiratory microbial genes. The catalog enables systematic exploration of taxonomic and functional variation across airway niches and geographic regions, revealing site‐specific and region ...
Qing Zhang   +15 more
wiley   +1 more source

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